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Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101721146, updated on 8-Mar-2024

Summary

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Gene symbol
Atp1a3
Gene description
ATPase Na+/K+ transporting subunit alpha 3
Locus tag
GW7_15424
See related
Ensembl:ENSHGLG00000004227
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624907.1 (715109..736040)

NW_004624907.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 574 Neighboring gene glutamate ionotropic receptor kainate type subunit 5 Neighboring gene Rab acceptor 1 Neighboring gene uncharacterized LOC110347266

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624907 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables P-type sodium:potassium-exchanging transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular potassium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular sodium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion export across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sodium/potassium-transporting ATPase subunit alpha-3
Names
Sodium/potassium-transporting ATPase subunit alpha-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624907.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    715109..736040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021250922.1 → XP_021106581.1  sodium/potassium-transporting ATPase subunit alpha-3 isoform X1

    UniProtKB/TrEMBL
    G5AZQ6
    Conserved Domains (1) summary
    TIGR01106
    Location:30 → 1026
    ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit

  2. XM_004873051.3 → XP_004873108.1  sodium/potassium-transporting ATPase subunit alpha-3 isoform X2

    Related
    ENSHGLP00000005780.1, ENSHGLT00000005853.1
    Conserved Domains (6) summary
    smart00831
    Location:30 → 104
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    COG4087
    Location:596 → 742
    COG4087; Soluble P-type ATPase [General function prediction only]
    TIGR01106
    Location:17 → 1013
    ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
    pfam00122
    Location:124 → 355
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:789 → 998
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam13246
    Location:417 → 511
    Cation_ATPase; Cation transport ATPase (P-type)
Nucleotide Protein
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