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PLEKHG5 pleckstrin homology and RhoGEF domain containing G5 [ Mustela putorius furo (domestic ferret) ]

Gene ID: 101692873, updated on 8-Mar-2024

Summary

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Gene symbol
PLEKHG5
Gene description
pleckstrin homology and RhoGEF domain containing G5
See related
Ensembl:ENSMPUG00000006788
Gene type
protein coding
RefSeq status
MODEL
Organism
Mustela putorius furo (sub-species: furo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025422005.1 (4027654..4053453, complement)
101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569279.1 (2714997..2739820)

NW_025422005.1Genomic Context describing neighboring genes Neighboring gene espin Neighboring gene TNF receptor superfamily member 25 Neighboring gene nucleolar protein 9 Neighboring gene taste 1 receptor member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing, annotation, and characterization of the influenza ferret infectome. León AJ, et al. J Virol, 2013 Feb. PMID 23236062, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endothelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endocytic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family G member 5
Names
pleckstrin-like proteiny domain containing, family G member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1176430v1.1 Primary Assembly

Genomic

  1. NW_025422005.1 Reference ASM1176430v1.1 Primary Assembly

    Range
    4027654..4053453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045063649.1 → XP_044919584.1  pleckstrin homology domain-containing family G member 5 isoform X3

    UniProtKB/TrEMBL
    A0A8U0ULU6, M3Y5Y3
    Conserved Domains (4) summary
    smart00325
    Location:389 → 576
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PHA03247
    Location:814 → 1037
    PHA03247; large tegument protein UL36; Provisional
    cd13244
    Location:632 → 730
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    cd17068
    Location:128 → 202
    RBD_PLEKHG5; Ras-binding domain (RBD) found in pleckstrin homology (PH) and RhoGEF domain containing G5 (PLEKHG5) and similar proteins

  2. XM_013064681.2 → XP_012920135.1  pleckstrin homology domain-containing family G member 5 isoform X4

    See identical proteins and their annotated locations for XP_012920135.1

    UniProtKB/TrEMBL
    A0A8U0P0I2, M3Y5Y3
    Conserved Domains (3) summary
    smart00325
    Location:333 → 520
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd13244
    Location:576 → 674
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00169
    Location:578 → 672
    PH; PH domain

  3. XM_013064679.2 → XP_012920133.1  pleckstrin homology domain-containing family G member 5 isoform X4

    See identical proteins and their annotated locations for XP_012920133.1

    UniProtKB/TrEMBL
    A0A8U0P0I2, M3Y5Y3
    Conserved Domains (3) summary
    smart00325
    Location:333 → 520
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd13244
    Location:576 → 674
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00169
    Location:578 → 672
    PH; PH domain

  4. XM_045063647.1 → XP_044919582.1  pleckstrin homology domain-containing family G member 5 isoform X1

    UniProtKB/TrEMBL
    A0A8U0R818, M3Y5Y3
    Conserved Domains (4) summary
    smart00325
    Location:396 → 583
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PHA03247
    Location:821 → 1044
    PHA03247; large tegument protein UL36; Provisional
    cd13244
    Location:639 → 737
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    cd17068
    Location:135 → 209
    RBD_PLEKHG5; Ras-binding domain (RBD) found in pleckstrin homology (PH) and RhoGEF domain containing G5 (PLEKHG5) and similar proteins

  5. XM_013064678.2 → XP_012920132.1  pleckstrin homology domain-containing family G member 5 isoform X5

    UniProtKB/TrEMBL
    A0A8U0P0W2, M3Y5Y3
    Conserved Domains (3) summary
    smart00325
    Location:288 → 475
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd13244
    Location:531 → 629
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00169
    Location:533 → 627
    PH; PH domain

  6. XM_045063650.1 → XP_044919585.1  pleckstrin homology domain-containing family G member 5 isoform X6

    UniProtKB/TrEMBL
    A0A8U0R8E2, M3Y5Y3
    Conserved Domains (4) summary
    smart00325
    Location:389 → 576
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PHA03247
    Location:814 → 1037
    PHA03247; large tegument protein UL36; Provisional
    cd13244
    Location:632 → 730
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    cd17068
    Location:128 → 202
    RBD_PLEKHG5; Ras-binding domain (RBD) found in pleckstrin homology (PH) and RhoGEF domain containing G5 (PLEKHG5) and similar proteins

  7. XM_045063648.1 → XP_044919583.1  pleckstrin homology domain-containing family G member 5 isoform X2

    UniProtKB/TrEMBL
    A0A8U0R6Y5, M3Y5Y3
    Conserved Domains (4) summary
    smart00325
    Location:396 → 583
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PHA03247
    Location:821 → 1044
    PHA03247; large tegument protein UL36; Provisional
    cd13244
    Location:639 → 737
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    cd17068
    Location:135 → 209
    RBD_PLEKHG5; Ras-binding domain (RBD) found in pleckstrin homology (PH) and RhoGEF domain containing G5 (PLEKHG5) and similar proteins
Nucleotide Protein
Heading Accession and Version

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