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HNF4A hepatocyte nuclear factor 4 alpha [ Mustela putorius furo (domestic ferret) ]

Gene ID: 101674295, updated on 8-Mar-2024

Summary

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Gene symbol
HNF4A
Gene description
hepatocyte nuclear factor 4 alpha
See related
Ensembl:ENSMPUG00000017669
Gene type
protein coding
RefSeq status
MODEL
Organism
Mustela putorius furo (sub-species: furo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025421426.1 (10134507..10196024, complement)
101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569160.1 (6574947..6636469, complement)

NW_025421426.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101671699 Neighboring gene serine incorporator 3 Neighboring gene alpha tocopherol transfer protein like Neighboring gene uncharacterized LOC106005270 Neighboring gene R3H domain containing like Neighboring gene fat storage inducing transmembrane protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear steroid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hepatocyte nuclear factor 4-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1176430v1.1 Primary Assembly

Genomic

  1. NW_025421426.1 Reference ASM1176430v1.1 Primary Assembly

    Range
    10134507..10196024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004746392.3 → XP_004746449.1  hepatocyte nuclear factor 4-alpha isoform X3

    UniProtKB/TrEMBL
    A0A8U0SSQ0, M3Z1U5
    Conserved Domains (2) summary
    cd06931
    Location:129 → 351
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:38 → 113
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  2. XM_045082172.1 → XP_044938107.1  hepatocyte nuclear factor 4-alpha isoform X5

    UniProtKB/TrEMBL
    A0A8U0S7Y4, M3Z1U5
    Conserved Domains (2) summary
    cd06931
    Location:59 → 281
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:2 → 43
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  3. XM_004746394.3 → XP_004746451.1  hepatocyte nuclear factor 4-alpha isoform X4

    UniProtKB/TrEMBL
    A0A8U0MM89, M3Z1U5
    Conserved Domains (2) summary
    cd06931
    Location:126 → 348
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:35 → 110
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  4. XM_004746390.3 → XP_004746447.1  hepatocyte nuclear factor 4-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8U0SSS7, M3Z1U5
    Conserved Domains (2) summary
    cd06931
    Location:151 → 373
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:60 → 135
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  5. XM_004746391.3 → XP_004746448.1  hepatocyte nuclear factor 4-alpha isoform X2

    UniProtKB/TrEMBL
    A0A8U0MLH1, M3Z1U5
    Related
    ENSMPUP00000017557.1
    Conserved Domains (2) summary
    cd06931
    Location:151 → 373
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:60 → 135
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
Nucleotide Protein
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