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ROCK1 Rho associated coiled-coil containing protein kinase 1 [ Condylura cristata (star-nosed mole) ]

Gene ID: 101628082, updated on 8-Mar-2024

Summary

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Gene symbol
ROCK1
Gene description
Rho associated coiled-coil containing protein kinase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Condylura cristata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Condylura
Orthologs
human mouse all
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Genomic context

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See ROCK1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
33
Annotation release Status Assembly Chr Location
101 current ConCri1.0 (GCF_000260355.1) Unplaced Scaffold NW_004567117.1 (11139306..11245466, complement)

NW_004567117.1Genomic Context describing neighboring genes Neighboring gene THO complex 1 Neighboring gene ubiquitin specific peptidase 14 Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene WD repeat-containing protein 61-like Neighboring gene GREB1 like retinoic acid receptor coactivator

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004567117.1 Unplaced Scaffold Reference ConCri1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Rho-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in embryonic morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho-associated protein kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Condylura cristata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ConCri1.0

Genomic

  1. NW_004567117.1 Reference ConCri1.0

    Range
    11139306..11245466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012725778.1 → XP_012581232.1  rho-associated protein kinase 1

    Conserved Domains (9) summary
    cd11639
    Location:449 → 514
    HR1_ROCK1; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase 1
    smart00220
    Location:76 → 298
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00029
    Location:1189 → 1243
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd01242
    Location:1079 → 1185
    PH_ROCK; Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain
    TIGR02168
    Location:410 → 1057
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cl21524
    Location:505 → 641
    PRK13923; putative spore coat protein regulator protein YlbO; Provisional
    pfam00169
    Location:1081 → 1168
    PH; PH domain
    pfam08912
    Location:909 → 974
    Rho_Binding; Rho Binding
    cl21453
    Location:2 → 366
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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