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Fxr2 FMR1 autosomal homolog 2 [ Octodon degus (degu) ]

Gene ID: 101587725, updated on 8-Mar-2024

Summary

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Gene symbol
Fxr2
Gene description
FMR1 autosomal homolog 2
See related
Ensembl:ENSODEG00000017803
Gene type
protein coding
RefSeq status
MODEL
Organism
Octodon degus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Octodontidae; Octodon
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
102 current OctDeg1.0 (GCF_000260255.1) Unplaced Scaffold NW_004524674.1 (5206479..5229956, complement)

NW_004524674.1Genomic Context describing neighboring genes Neighboring gene mannose-P-dolichol utilization defect 1 Neighboring gene SRY-box transcription factor 15 Neighboring gene U6 spliceosomal RNA Neighboring gene spermidine/spermine N1-acetyltransferase family member 2 Neighboring gene sex hormone binding globulin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004524674 Unplaced Scaffold Reference OctDeg1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterograde axonal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of filopodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mRNA stability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of modification of synaptic structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of translation at postsynapse, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic filopodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine neck IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: fragile X mental retardation syndrome-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Octodon degus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OctDeg1.0 Primary Assembly

Genomic

  1. NW_004524674.1 Reference OctDeg1.0 Primary Assembly

    Range
    5206479..5229956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004649080.2 → XP_004649137.1  LOW QUALITY PROTEIN: fragile X mental retardation syndrome-related protein 2

    UniProtKB/TrEMBL
    A0A6P3G127
    Related
    ENSODEP00000024330.1, ENSODET00000024605.1
    Conserved Domains (5) summary
    smart00322
    Location:233 → 293
    KH; K homology RNA-binding domain
    cd00105
    Location:299 → 365
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:72 → 129
    Agenet; Agenet domain
    pfam12235
    Location:367 → 467
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:512 → 579
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
Nucleotide Protein
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