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Nefl neurofilament light chain [ Octodon degus (degu) ]

Gene ID: 101577546, updated on 8-Mar-2024

Summary

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Gene symbol
Nefl
Gene description
neurofilament light chain
See related
Ensembl:ENSODEG00000007183
Gene type
protein coding
RefSeq status
MODEL
Organism
Octodon degus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Octodontidae; Octodon
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
102 current OctDeg1.0 (GCF_000260255.1) Unplaced Scaffold NW_004524612.1 (11146127..11151347, complement)

NW_004524612.1Genomic Context describing neighboring genes Neighboring gene U6atac minor spliceosomal RNA Neighboring gene neurofilament medium chain Neighboring gene dedicator of cytokinesis 5 Neighboring gene gonadotropin releasing hormone 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004524612 Unplaced Scaffold Reference OctDeg1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables structural constituent of postsynaptic intermediate filament cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in neurofilament bundle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic intermediate filament cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurofilament light polypeptide
Names
neurofilament, light polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Octodon degus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OctDeg1.0 Primary Assembly

Genomic

  1. NW_004524612.1 Reference OctDeg1.0 Primary Assembly

    Range
    11146127..11151347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023714729.1 → XP_023570497.1  neurofilament light polypeptide isoform X2

    UniProtKB/TrEMBL
    A0A6P6EEK2
    Conserved Domains (2) summary
    pfam00038
    Location:89 → 400
    Filament; Intermediate filament protein
    pfam04732
    Location:9 → 88
    Filament_head; Intermediate filament head (DNA binding) region

  2. XM_004630670.2 → XP_004630727.1  neurofilament light polypeptide isoform X1

    UniProtKB/TrEMBL
    A0A6P3ERZ9
    Related
    ENSODEP00000009602.1, ENSODET00000009745.1
    Conserved Domains (4) summary
    pfam00038
    Location:89 → 400
    Filament; Intermediate filament protein
    pfam04732
    Location:9 → 88
    Filament_head; Intermediate filament head (DNA binding) region
    cd16269
    Location:212 → 222
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:140 → 239
    GBP_C; Guanylate-binding protein, C-terminal domain
Nucleotide Protein
Heading Accession and Version

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