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Braf B-Raf proto-oncogene, serine/threonine kinase [ Octodon degus (degu) ]

Gene ID: 101563215, updated on 8-Mar-2024

Summary

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Gene symbol
Braf
Gene description
B-Raf proto-oncogene, serine/threonine kinase
See related
Ensembl:ENSODEG00000013401
Gene type
protein coding
RefSeq status
MODEL
Organism
Octodon degus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Octodontidae; Octodon
Orthologs
human mouse all
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Genomic context

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See Braf in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
102 current OctDeg1.0 (GCF_000260255.1) Unplaced Scaffold NW_004524603.1 (15182706..15358371)

NW_004524603.1Genomic Context describing neighboring genes Neighboring gene guanine nucleotide-binding protein-like 3-like protein Neighboring gene mitochondrial ribosomal protein S33 Neighboring gene small nucleolar RNA U13 Neighboring gene serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit B2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004524603 Unplaced Scaffold Reference OctDeg1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase B-raf
Names
v-raf murine sarcoma viral oncogene homolog B1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Octodon degus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OctDeg1.0 Primary Assembly

Genomic

  1. NW_004524603.1 Reference OctDeg1.0 Primary Assembly

    Range
    15182706..15358371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023712827.1 → XP_023568595.1  serine/threonine-protein kinase B-raf isoform X3

    UniProtKB/TrEMBL
    A0A6P6E8E1
    Conserved Domains (3) summary
    cd01816
    Location:152 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:422 → 668
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  2. XM_023712830.1 → XP_023568598.1  serine/threonine-protein kinase B-raf isoform X7

    UniProtKB/TrEMBL
    A0A6P6E978
    Conserved Domains (3) summary
    cd14062
    Location:374 → 620
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:146 → 191
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    cl00155
    Location:77 → 138
    UBQ; Ubiquitin-like proteins

  3. XM_023712825.1 → XP_023568593.1  serine/threonine-protein kinase B-raf isoform X1

    UniProtKB/TrEMBL
    A0A6P6E972
    Conserved Domains (3) summary
    cd01816
    Location:152 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 708
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  4. XM_023712829.1 → XP_023568597.1  serine/threonine-protein kinase B-raf isoform X5

    UniProtKB/TrEMBL
    A0A6P6E923
    Conserved Domains (3) summary
    cd01816
    Location:152 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    cl21453
    Location:462 → 664
    PKc_like; Protein Kinases, catalytic domain

  5. XM_023712826.1 → XP_023568594.1  serine/threonine-protein kinase B-raf isoform X2

    UniProtKB/TrEMBL
    A0A6P6E8B7
    Conserved Domains (3) summary
    cd01816
    Location:152 → 223
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:459 → 705
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:231 → 276
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  6. XM_023712828.1 → XP_023568596.1  serine/threonine-protein kinase B-raf isoform X4

    UniProtKB/TrEMBL
    A0A6P6E8Q6
    Related
    ENSODEP00000018183.1, ENSODET00000018414.1
    Conserved Domains (3) summary
    cd01816
    Location:152 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 714
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  7. XM_023712831.1 → XP_023568599.1  serine/threonine-protein kinase B-raf isoform X8

    UniProtKB/TrEMBL
    A0A6P6E8C2
    Related
    ENSODEP00000018182.1, ENSODET00000018413.1
    Conserved Domains (3) summary
    cd01816
    Location:152 → 223
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:499 → 751
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:231 → 276
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  8. XM_004629038.3 → XP_004629095.2  serine/threonine-protein kinase B-raf isoform X6

    UniProtKB/TrEMBL
    A0A6P3F012
    Conserved Domains (3) summary
    cd01816
    Location:152 → 223
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:459 → 711
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:231 → 276
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
Nucleotide Protein
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