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Rasgrf2 Ras protein specific guanine nucleotide releasing factor 2 [ Octodon degus (degu) ]

Gene ID: 101560661, updated on 8-Mar-2024

Summary

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Gene symbol
Rasgrf2
Gene description
Ras protein specific guanine nucleotide releasing factor 2
See related
Ensembl:ENSODEG00000004227
Gene type
protein coding
RefSeq status
MODEL
Organism
Octodon degus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Octodontidae; Octodon
Orthologs
human mouse all
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Genomic context

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See Rasgrf2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current OctDeg1.0 (GCF_000260255.1) Unplaced Scaffold NW_004524705.1 (1282000..1463239)

NW_004524705.1Genomic Context describing neighboring genes Neighboring gene dihydrofolate reductase Neighboring gene mutS homolog 3 Neighboring gene creatine kinase, mitochondrial 2 Neighboring gene zinc finger CCHC-type containing 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004524705 Unplaced Scaffold Reference OctDeg1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-specific guanine nucleotide-releasing factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Octodon degus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OctDeg1.0 Primary Assembly

Genomic

  1. NW_004524705.1 Reference OctDeg1.0 Primary Assembly

    Range
    1282000..1463239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004640933.2 → XP_004640990.1  ras-specific guanine nucleotide-releasing factor 2

    UniProtKB/TrEMBL
    A0A6P3FN22
    Related
    ENSODEP00000005597.1, ENSODET00000005696.1
    Conserved Domains (7) summary
    smart00147
    Location:957 → 1193
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00233
    Location:480 → 588
    PH; Pleckstrin homology domain
    cd13261
    Location:19 → 158
    PH_RasGRF1_2; Ras-specific guanine nucleotide-releasing factors 1 and 2 Pleckstrin homology (PH) domain
    pfam00169
    Location:24 → 133
    PH; PH domain
    pfam00618
    Location:638 → 687
    RasGEF_N; RasGEF N-terminal motif
    pfam00621
    Location:247 → 428
    RhoGEF; RhoGEF domain
    cl02520
    Location:863 → 928
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
Nucleotide Protein
Heading Accession and Version

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