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OTX2 orthodenticle homeobox 2 [ Sorex araneus (European shrew) ]

Gene ID: 101545372, updated on 8-Mar-2024

Summary

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Gene symbol
OTX2
Gene description
orthodenticle homeobox 2
See related
EnsemblRapid:ENSSARG00000030555
Gene type
protein coding
RefSeq status
MODEL
Organism
Sorex araneus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae; Soricinae; Sorex
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_04 current mSorAra2.pri (GCF_027595985.1) 3 NC_073304.1 (43100208..43110107)
101 previous assembly SorAra2.0 (GCF_000181275.1) Unplaced Scaffold NW_004545859.1 (41623689..41628522, complement)

Chromosome 3 - NC_073304.1Genomic Context describing neighboring genes Neighboring gene exocyst complex component 5 Neighboring gene 60S ribosomal protein L34-like Neighboring gene transmembrane protein 260 Neighboring gene small nucleolar RNA SNORA1 Neighboring gene pellino E3 ubiquitin protein ligase family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
homeobox protein OTX2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027595985.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSorAra2.pri

Genomic

  1. NC_073304.1 Reference mSorAra2.pri

    Range
    43100208..43110107
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055131997.1 → XP_054987972.1  homeobox protein OTX2 isoform X1

  2. XM_004601772.2 → XP_004601829.1  homeobox protein OTX2 isoform X2

    See identical proteins and their annotated locations for XP_004601829.1

    Related
    ENSSARP00000014216.1, ENSSART00000032235.1
    Conserved Domains (2) summary
    pfam00046
    Location:42 → 94
    Homeobox; Homeobox domain
    pfam03529
    Location:155 → 234
    TF_Otx; Otx1 transcription factor

  3. XM_055131998.1 → XP_054987973.1  homeobox protein OTX2 isoform X1

  4. XM_004601771.2 → XP_004601828.1  homeobox protein OTX2 isoform X1

    See identical proteins and their annotated locations for XP_004601828.1

    Related
    ENSSARP00000015346.1, ENSSART00000042120.1
    Conserved Domains (2) summary
    pfam00046
    Location:50 → 102
    Homeobox; Homeobox domain
    pfam03529
    Location:163 → 242
    TF_Otx; Otx1 transcription factor

  5. XM_055132000.1 → XP_054987975.1  homeobox protein OTX2 isoform X1

Nucleotide Protein
Heading Accession and Version

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