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DUSP1 dual specificity phosphatase 1 [ Ochotona princeps (American pika) ]

Gene ID: 101531665, updated on 8-Mar-2024

Summary

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Gene symbol
DUSP1
Gene description
dual specificity phosphatase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Ochotona princeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_07 current mOchPri1.hap1 (GCF_030435755.1) 19 NC_080850.1 (5600165..5602553)
102 previous assembly OchPri4.0 (GCF_014633375.1) 3A NC_050561.1 (5329557..5332364)

Chromosome 19 - NC_080850.1Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V0 subunit e1 Neighboring gene endoplasmic reticulum-golgi intermediate compartment 1 Neighboring gene neuralized E3 ubiquitin protein ligase 1B Neighboring gene SH3 and PX domains 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoderm formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of p38MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030435755.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOchPri1.hap1

Genomic

  1. NC_080850.1 Reference mOchPri1.hap1

    Range
    5600165..5602553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004587422.3 → XP_004587479.1  dual specificity protein phosphatase 1

    Conserved Domains (3) summary
    COG2453
    Location:188 → 313
    CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]
    cd00127
    Location:173 → 309
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
    cd01446
    Location:7 → 136
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
Nucleotide Protein
Heading Accession and Version

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