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HECTD1 HECT domain E3 ubiquitin protein ligase 1 [ Ochotona princeps (American pika) ]

Gene ID: 101531505, updated on 8-Mar-2024

Summary

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Gene symbol
HECTD1
Gene description
HECT domain E3 ubiquitin protein ligase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Ochotona princeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
43
Annotation release Status Assembly Chr Location
RS_2023_07 current mOchPri1.hap1 (GCF_030435755.1) 6 NC_080837.1 (53189771..53266305, complement)
102 previous assembly OchPri4.0 (GCF_014633375.1) 17 NC_050552.1 (37549610..37626302)

Chromosome 6 - NC_080837.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL33-like Neighboring gene cochlin Neighboring gene striatin 3 Neighboring gene adaptor related protein complex 4 subunit sigma 1 Neighboring gene HEAT repeat containing 5A Neighboring gene D-aminoacyl-tRNA deacylase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase HECTD1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030435755.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOchPri1.hap1

Genomic

  1. NC_080837.1 Reference mOchPri1.hap1

    Range
    53189771..53266305 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_058666292.1 → XP_058522275.1  E3 ubiquitin-protein ligase HECTD1 isoform X3

  2. XM_004584741.4 → XP_004584798.1  E3 ubiquitin-protein ligase HECTD1 isoform X1

    Conserved Domains (7) summary
    smart00119
    Location:2155 → 2607
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd00078
    Location:2131 → 2608
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    cd00204
    Location:369 → 479
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam06701
    Location:1277 → 1335
    MIB_HERC2; Mib_herc2
    pfam12796
    Location:366 → 457
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:396 → 426
    ANK; ANK repeat [structural motif]
    cl23730
    Location:1107 → 1240
    F5_F8_type_C; F5/8 type C domain

  3. XM_058666293.1 → XP_058522276.1  E3 ubiquitin-protein ligase HECTD1 isoform X4

  4. XM_058666296.1 → XP_058522279.1  E3 ubiquitin-protein ligase HECTD1 isoform X7

  5. XM_058666295.1 → XP_058522278.1  E3 ubiquitin-protein ligase HECTD1 isoform X6

  6. XM_058666291.1 → XP_058522274.1  E3 ubiquitin-protein ligase HECTD1 isoform X2

  7. XM_058666294.1 → XP_058522277.1  E3 ubiquitin-protein ligase HECTD1 isoform X5

  8. XM_058666289.1 → XP_058522272.1  E3 ubiquitin-protein ligase HECTD1 isoform X1

  9. XM_058666298.1 → XP_058522281.1  E3 ubiquitin-protein ligase HECTD1 isoform X9

  10. XM_058666297.1 → XP_058522280.1  E3 ubiquitin-protein ligase HECTD1 isoform X8

Nucleotide Protein
Heading Accession and Version

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