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abl1 c-abl oncogene 1, non-receptor tyrosine kinase [ Maylandia zebra (zebra mbuna) ]

Gene ID: 101475377, updated on 8-Mar-2024

Summary

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Gene symbol
abl1
Gene description
c-abl oncogene 1, non-receptor tyrosine kinase
See related
Ensembl:ENSMZEG00005018744
Gene type
protein coding
RefSeq status
MODEL
Organism
Maylandia zebra
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG7
Exon count:
13
Annotation release Status Assembly LG Location
104 current M_zebra_UMD2a (GCF_000238955.4) LG7 NC_036786.1 (43577848..43611821)
101 previous assembly MetZeb1.1 (GCF_000238955.1) Unplaced Scaffold NW_004531711.1 (5365080..5399251, complement)

Linkage Group LG7 - NC_036786.1Genomic Context describing neighboring genes Neighboring gene RIC1 homolog, RAB6A GEF complex partner 1 Neighboring gene exosome component 2 Neighboring gene RAB14, member RAS oncogene family, like Neighboring gene ATP-dependent RNA helicase DDX54 Neighboring gene transfer RNA cysteine (anticodon GCA)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ABL1
Names
ABL proto-oncogene 1, non-receptor tyrosine kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Maylandia zebra Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference M_zebra_UMD2a Primary Assembly

Genomic

  1. NC_036786.1 Reference M_zebra_UMD2a Primary Assembly

    Range
    43577848..43611821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012916721.4 → XP_012772175.1  tyrosine-protein kinase ABL1 isoform X1

    See identical proteins and their annotated locations for XP_012772175.1

    UniProtKB/TrEMBL
    A0A3P9CRZ9
    Related
    ENSMZEP00005025108.1, ENSMZET00005025926.1
    Conserved Domains (4) summary
    smart00808
    Location:979 → 1104
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:136 → 229
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:78 → 131
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:248 → 510
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  2. XM_012916722.4 → XP_012772176.1  tyrosine-protein kinase ABL1 isoform X1

    See identical proteins and their annotated locations for XP_012772176.1

    UniProtKB/TrEMBL
    A0A3P9CRZ9
    Conserved Domains (4) summary
    smart00808
    Location:979 → 1104
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:136 → 229
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:78 → 131
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:248 → 510
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  3. XM_012916725.4 → XP_012772179.1  tyrosine-protein kinase ABL1 isoform X2

    UniProtKB/TrEMBL
    A0A3P9CS06
    Related
    ENSMZEP00005025118.1, ENSMZET00005025936.1
    Conserved Domains (4) summary
    smart00808
    Location:965 → 1090
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:122 → 215
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:64 → 117
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:234 → 496
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
Nucleotide Protein
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