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TIMP3 TIMP metallopeptidase inhibitor 3 [ Dasypus novemcinctus (nine-banded armadillo) ]

Gene ID: 101440761, updated on 8-Mar-2024

Summary

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Gene symbol
TIMP3
Gene description
TIMP metallopeptidase inhibitor 3
See related
Ensembl:ENSDNOG00000007763
Gene type
protein coding
RefSeq status
MODEL
Organism
Dasypus novemcinctus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Xenarthra; Cingulata; Dasypodidae; Dasypus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_07 current mDasNov1.hap2 (GCF_030445035.1) 12 NC_080684.1 (92789394..92844103)
102 previous assembly Dasnov3.0 (GCF_000208655.1) Unplaced Scaffold NW_004497759.1 (715390..766833)

Chromosome 12 - NC_080684.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111761221 Neighboring gene synapsin III Neighboring gene uncharacterized LOC111761222 Neighboring gene dynein axonemal assembly factor 10-like Neighboring gene protein-tyrosine sulfotransferase 2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to organic substance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metalloproteinase inhibitor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030445035.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mDasNov1.hap2

Genomic

  1. NC_080684.1 Reference mDasNov1.hap2

    Range
    92789394..92844103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004480814.4 → XP_004480871.1  metalloproteinase inhibitor 3

    UniProtKB/TrEMBL
    C3PSY3
    Related
    ENSDNOP00000006018.2
    Conserved Domains (1) summary
    cd03585
    Location:24 → 200
    NTR_TIMP; NTR domain, TIMP subfamily; TIMPs, or tissue inibitors of metalloproteases, are essential regulators of extracellular matrix turnover and remodeling. They form complexes with matrix metalloproteases (MMPs) and inactivate them irreversibly by ...
Nucleotide Protein
Heading Accession and Version

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