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FGA fibrinogen alpha chain [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101385350, updated on 8-Mar-2024

Summary

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Gene symbol
FGA
Gene description
fibrinogen alpha chain
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450292.1 (4841886..4850143)

NW_004450292.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene fibrinogen gamma chain Neighboring gene fibrinogen beta chain Neighboring gene pleiotropic regulator 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450292.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in blood coagulation, common pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fibrinolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of endothelial cell apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet aggregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptide hormone secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of fibrinogen complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibrinogen alpha chain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450292.1 Reference Oros_1.0 Primary Assembly

    Range
    4841886..4850143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004394257.2 → XP_004394314.1  fibrinogen alpha chain

    UniProtKB/TrEMBL
    A0A2U3VHL6
    Conserved Domains (3) summary
    cd00087
    Location:634 → 867
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam08702
    Location:50 → 189
    Fib_alpha; Fibrinogen alpha/beta chain family
    pfam12160
    Location:457 → 517
    Fibrinogen_aC; Fibrinogen alpha C domain
Nucleotide Protein
Heading Accession and Version

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