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NPR2 natriuretic peptide receptor 2 [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101385033, updated on 8-Mar-2024

Summary

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Gene symbol
NPR2
Gene description
natriuretic peptide receptor 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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See NPR2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450270.1 (3014493..3030850)

NW_004450270.1Genomic Context describing neighboring genes Neighboring gene cAMP responsive element binding protein 3 Neighboring gene glucosylceramidase beta 2 Neighboring gene RGP1 homolog, RAB6A GEF complex partner 1 Neighboring gene microseminoprotein, prostate associated Neighboring gene sperm associated antigen 8 Neighboring gene histidine triad nucleotide binding protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450270.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables natriuretic peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cGMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor guanylyl cyclase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
atrial natriuretic peptide receptor 2
Names
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450270.1 Reference Oros_1.0 Primary Assembly

    Range
    3014493..3030850
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012562016.1 → XP_012417470.1  atrial natriuretic peptide receptor 2 isoform X2

    Conserved Domains (6) summary
    smart00044
    Location:787 → 971
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:480 → 754
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam00211
    Location:814 → 1000
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam01094
    Location:44 → 359
    ANF_receptor; Receptor family ligand binding region
    pfam07701
    Location:763 → 808
    HNOBA; Heme NO binding associated
    cl10011
    Location:26 → 383
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

  2. XM_004392264.2 → XP_004392321.1  atrial natriuretic peptide receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A2U3VCL8
    Conserved Domains (4) summary
    smart00044
    Location:825 → 1009
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:518 → 792
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam07701
    Location:801 → 846
    HNOBA; Heme NO binding associated
    cl10011
    Location:26 → 421
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version

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