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ALS2 alsin Rho guanine nucleotide exchange factor ALS2 [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101363756, updated on 8-Mar-2024

Summary

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Gene symbol
ALS2
Gene description
alsin Rho guanine nucleotide exchange factor ALS2
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450280.1 (1167417..1241960)

NW_004450280.1Genomic Context describing neighboring genes Neighboring gene frizzled class receptor 7 Neighboring gene cyclin dependent kinase 15 Neighboring gene MAGUK p55 scaffold protein 4 Neighboring gene transmembrane protein 237

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450280.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alsin
Names
ALS2, alsin Rho guanine nucleotide exchange factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450280.1 Reference Oros_1.0 Primary Assembly

    Range
    1167417..1241960
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004393461.1 → XP_004393518.1  alsin

    UniProtKB/TrEMBL
    A0A2U3VFM5
    Conserved Domains (8) summary
    COG4642
    Location:1049 → 1188
    COG4642; Uncharacterized conserved protein [Function unknown]
    cd13269
    Location:905 → 1010
    PH_alsin; Alsin Pleckstrin homology (PH) domain
    pfam00169
    Location:926 → 1004
    PH; PH domain
    pfam00415
    Location:527 → 574
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam02204
    Location:1554 → 1653
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
    pfam02493
    Location:1100 → 1120
    MORN; MORN repeat
    pfam13540
    Location:93 → 122
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cl02571
    Location:695 → 879
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
Nucleotide Protein
Heading Accession and Version

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