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RET ret proto-oncogene [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101339908, updated on 11-Apr-2024

Summary

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Gene symbol
RET
Gene description
ret proto-oncogene
See related
EnsemblRapid:ENSTTRG00000001614
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
19
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 16 NC_047049.1 (72843911..72902252, complement)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017843227.1 (5390334..5473094, complement)

Chromosome 16 - NC_047049.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117308508 Neighboring gene FXYD domain containing ion transport regulator 4 Neighboring gene RasGEF domain family member 1A Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2 Neighboring gene zinc finger protein 33B-like Neighboring gene zinc finger protein 33B-like Neighboring gene BMS1 ribosome biogenesis factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene tyrosine-protein kinase receptor Ret

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047049.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    72843911..72902252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033842157.1 → XP_033698048.1  proto-oncogene tyrosine-protein kinase receptor Ret

    UniProtKB/TrEMBL
    A0A6J3Q7G4
    Related
    ENSTTRP00000001522.1, ENSTTRT00000001615.2
    Conserved Domains (5) summary
    cd05045
    Location:722 → 1011
    PTKc_RET; Catalytic domain of the Protein Tyrosine Kinase, REarranged during Transfection protein
    pfam00028
    Location:171 → 259
    Cadherin; Cadherin domain
    pfam17756
    Location:27 → 152
    RET_CLD1; RET Cadherin like domain 1
    pfam17812
    Location:263 → 377
    RET_CLD3; RET Cadherin like domain 3
    pfam17813
    Location:419 → 504
    RET_CLD4; RET Cadherin like domain 4
Nucleotide Protein
Heading Accession and Version

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