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NGLY1 N-glycanase 1 [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101337856, updated on 8-Mar-2024

Summary

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Gene symbol
NGLY1
Gene description
N-glycanase 1
See related
EnsemblRapid:ENSTTRG00000014979
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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See NGLY1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 4 NC_047037.1 (1298360..1361218)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017844191.1 (4793653..4850707, complement)

Chromosome 4 - NC_047037.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L23a-like Neighboring gene 3-oxoacyl-ACP synthase, mitochondrial Neighboring gene DNA topoisomerase II beta Neighboring gene retinoic acid receptor beta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycoprotein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein deglycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047037.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    1298360..1361218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019948623.2 → XP_019804182.2  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X3

    UniProtKB/TrEMBL
    A0A2U4CFG2
    Related
    ENSTTRP00000014202.2, ENSTTRT00000014981.2
    Conserved Domains (4) summary
    cd10459
    Location:17 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:267 → 355
    Transglut_core; Transglutaminase-like superfamily
    cl10509
    Location:458 → 539
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl10615
    Location:339 → 423
    sm_acid_XPC-like; small acidic domain of Xeroderma pigmentosum group C complementing protein and similar proteins

  2. XM_019948621.2 → XP_019804180.2  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X1

    UniProtKB/TrEMBL
    A0A2U4CFL4
    Related
    ENSTTRP00000018921.1, ENSTTRT00000043836.1
    Conserved Domains (4) summary
    cd10459
    Location:17 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:267 → 355
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:458 → 652
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl10615
    Location:339 → 423
    sm_acid_XPC-like; small acidic domain of Xeroderma pigmentosum group C complementing protein and similar proteins

  3. XM_019948622.2 → XP_019804181.2  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X2

    UniProtKB/TrEMBL
    A0A2U4CFG3
    Conserved Domains (4) summary
    pfam01841
    Location:190 → 278
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:381 → 575
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl10615
    Location:262 → 346
    sm_acid_XPC-like; small acidic domain of Xeroderma pigmentosum group C complementing protein and similar proteins
    cl15262
    Location:1 → 32
    PUB; PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins
Nucleotide Protein
Heading Accession and Version

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