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LRRK1 leucine rich repeat kinase 1 [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101337173, updated on 8-Mar-2024

Summary

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Gene symbol
LRRK1
Gene description
leucine rich repeat kinase 1
See related
EnsemblRapid:ENSTTRG00000005190
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
38
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 2 NC_047035.1 (124673430..124794561, complement)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017843947.1 (22010949..22121474)

Chromosome 2 - NC_047035.1Genomic Context describing neighboring genes Neighboring gene chondroitin sulfate synthase 1 Neighboring gene polyadenylate-binding protein 2-like Neighboring gene 60S ribosomal protein L39-like Neighboring gene aldehyde dehydrogenase 1 family member A3 Neighboring gene ankyrin repeat and SOCS box containing 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leucine-rich repeat serine/threonine-protein kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047035.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    124673430..124794561 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033852062.1 → XP_033707953.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6J3R1K8
    Conserved Domains (8) summary
    PLN00113
    Location:446 → 603
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:262 → 517
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1256 → 1531
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:282 → 304
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:157 → 187
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:92 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:845 → 1037
    COR; C-terminal of Roc, COR, domain
    cl38936
    Location:640 → 822
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_033852063.1 → XP_033707954.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A6J3R0E4
    Related
    ENSTTRP00000004908.2, ENSTTRT00000005204.2
    Conserved Domains (8) summary
    PLN00113
    Location:446 → 603
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:262 → 517
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1249 → 1524
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:282 → 304
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:157 → 187
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:92 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:845 → 1037
    COR; C-terminal of Roc, COR, domain
    cl38936
    Location:640 → 822
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_033852061.1 → XP_033707952.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6J3R1K8
    Conserved Domains (8) summary
    PLN00113
    Location:446 → 603
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:262 → 517
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1256 → 1531
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:282 → 304
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:157 → 187
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:92 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:845 → 1037
    COR; C-terminal of Roc, COR, domain
    cl38936
    Location:640 → 822
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_033852064.1 → XP_033707955.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A6J3QZM5
    Conserved Domains (6) summary
    PLN00113
    Location:197 → 354
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:13 → 268
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1007 → 1282
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:33 → 55
    LRR_RI; leucine-rich repeat [structural motif]
    pfam16095
    Location:596 → 788
    COR; C-terminal of Roc, COR, domain
    cl38936
    Location:391 → 573
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  5. XM_033852065.1 → XP_033707956.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A6J3QZY1
    Conserved Domains (8) summary
    PLN00113
    Location:446 → 603
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:262 → 517
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1256 → 1531
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:282 → 304
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:157 → 187
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:92 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:845 → 1037
    COR; C-terminal of Roc, COR, domain
    cl38936
    Location:640 → 822
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  6. XM_033852066.1 → XP_033707957.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X5

    UniProtKB/TrEMBL
    A0A6J3R0C2
    Conserved Domains (8) summary
    PLN00113
    Location:446 → 603
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:262 → 517
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1256 → 1531
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:282 → 304
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:157 → 187
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:92 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam16095
    Location:845 → 1037
    COR; C-terminal of Roc, COR, domain
    cl38936
    Location:640 → 822
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
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