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JAG1 jagged canonical Notch ligand 1 [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101323540, updated on 8-Mar-2024

Summary

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Gene symbol
JAG1
Gene description
jagged canonical Notch ligand 1
See related
EnsemblRapid:ENSTTRG00000006190
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
26
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 15 NC_047048.1 (49639782..49675404)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017843589.1 (2765561..2801160)

Chromosome 15 - NC_047048.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109550914 Neighboring gene histidine triad nucleotide-binding protein 2, mitochondrial-like Neighboring gene SLX4 interacting protein Neighboring gene MKKS centrosomal shuttling protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Notch binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell communication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of protein-containing complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein jagged-1
Names
jagged 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047048.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    49639782..49675404
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004322269.3 → XP_004322317.3  protein jagged-1 isoform X1

    UniProtKB/TrEMBL
    A0A2U3V5R6
    Related
    ENSTTRP00000018346.1, ENSTTRT00000029484.1

  2. XM_019941431.2 → XP_019796990.2  protein jagged-1 isoform X2

    UniProtKB/TrEMBL
    A0A2U4BUW3
    Conserved Domains (6) summary
    smart00179
    Location:525 → 562
    EGF_CA; Calcium-binding EGF-like domain
    smart00215
    Location:846 → 913
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:612 → 648
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:731 → 760
    EGF; EGF-like domain
    pfam01414
    Location:167 → 229
    DSL; Delta serrate ligand
    pfam07657
    Location:32 → 107
    MNNL; N-terminus of Notch ligand
Nucleotide Protein
Heading Accession and Version

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