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CRK CRK proto-oncogene, adaptor protein [ Orcinus orca (killer whale) ]

Gene ID: 101284062, updated on 8-Mar-2024

Summary

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Gene symbol
CRK
Gene description
CRK proto-oncogene, adaptor protein
See related
EnsemblRapid:ENSOORG00010009174
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 19 NC_064577.1 (7503962..7529780, complement)

Chromosome 19 - NC_064577.1Genomic Context describing neighboring genes Neighboring gene double C2 domain beta Neighboring gene uncharacterized LOC117200404 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Neighboring gene uncharacterized LOC117200403 Neighboring gene myosin IC

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064577.1 Chromosome 19 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adapter molecule crk
Names
v-crk sarcoma virus CT10 oncogene homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064577.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    7503962..7529780 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004267075.3 → XP_004267123.1  adapter molecule crk isoform X2

    See identical proteins and their annotated locations for XP_004267123.1

    Conserved Domains (2) summary
    cd09926
    Location:5 → 122
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:135 → 189
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

  2. XM_004267074.3 → XP_004267122.1  adapter molecule crk isoform X1

    See identical proteins and their annotated locations for XP_004267122.1

    Related
    ENSOORP00010011353.1, ENSOORT00010013453.1
    Conserved Domains (3) summary
    cd09926
    Location:5 → 122
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:135 → 189
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

  3. XM_033423291.2 → XP_033279182.1  adapter molecule crk isoform X3

    Conserved Domains (3) summary
    cd11758
    Location:102 → 156
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:204 → 260
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cl15255
    Location:48 → 89
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
Heading Accession and Version

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