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LOC101145975 procathepsin L [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101145975, updated on 14-Mar-2024

Summary

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Gene symbol
LOC101145975
Gene description
procathepsin L
See related
Ensembl:ENSGGOG00000027208
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Also known as
CTSL
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Genomic context

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Location:
chromosome: 13
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 13 NC_073237.2 (83934614..83940514)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 9 NC_073233.1 (84441339..84446674)

Chromosome 13 - NC_073237.2Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit NDUFA4-like Neighboring gene small ribosomal subunit protein uS14-like Neighboring gene death associated protein kinase 1 Neighboring gene eukaryotic translation initiation factor 3 subunit J-like Neighboring gene putative inactive cathepsin L-like protein CTSL3P Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activator activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
procathepsin L
Names
cathepsin L
cathepsin L1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073237.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    83934614..83940514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019033498.4 → XP_018889043.2  procathepsin L

    UniProtKB/TrEMBL
    G3SEM1
    Conserved Domains (2) summary
    smart00848
    Location:29 → 87
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:114 → 332
    Peptidase_C1; Papain family cysteine protease

  2. XM_019033499.4 → XP_018889044.2  procathepsin L

    UniProtKB/TrEMBL
    G3SEM1
    Conserved Domains (2) summary
    smart00848
    Location:29 → 87
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:114 → 332
    Peptidase_C1; Papain family cysteine protease

  3. XM_019033500.4 → XP_018889045.2  procathepsin L

    UniProtKB/TrEMBL
    G3SEM1
    Conserved Domains (2) summary
    smart00848
    Location:29 → 87
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:114 → 332
    Peptidase_C1; Papain family cysteine protease

  4. XM_019033501.4 → XP_018889046.2  procathepsin L

    UniProtKB/TrEMBL
    G3SEM1
    Conserved Domains (2) summary
    smart00848
    Location:29 → 87
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:114 → 332
    Peptidase_C1; Papain family cysteine protease
Nucleotide Protein
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