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PLXNA1 plexin A1 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101141847, updated on 14-Mar-2024

Summary

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Gene symbol
PLXNA1
Gene description
plexin A1
See related
Ensembl:ENSGGOG00000000847
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 2 NC_086017.1 (138157750..138212054)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 3 NC_073227.1 (138015524..138069791)

Chromosome 2 - NC_086017.1Genomic Context describing neighboring genes Neighboring gene splicing factor 3A subunit 2-like Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 6 Neighboring gene protein RCC2-like Neighboring gene proline-rich protein 23E-like Neighboring gene PRR23 family member E

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of semaphorin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plexin-A1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_086017.1 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    138157750..138212054
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031009365.3 → XP_030865225.1  plexin-A1

    UniProtKB/TrEMBL
    G3S0Z9
    Conserved Domains (10) summary
    cd11271
    Location:57 → 532
    Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
    smart00423
    Location:534 → 566
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd01179
    Location:980 → 1065
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:883 → 979
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1067 → 1167
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01437
    Location:679 → 726
    PSI; Plexin repeat
    pfam01833
    Location:1169 → 1253
    TIG; IPT/TIG domain
    pfam08337
    Location:1337 → 1884
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
    pfam17960
    Location:589 → 678
    TIG_plexin; TIG domain
    pfam18020
    Location:732 → 826
    TIG_2; TIG domain found in plexin
Nucleotide Protein
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