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AGT angiotensinogen [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101141078, updated on 14-Mar-2024

Summary

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Gene symbol
AGT
Gene description
angiotensinogen
See related
Ensembl:ENSGGOG00000000197
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Also known as
SERPINA8
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 1 NC_073224.2 (19420796..19431827, complement)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 1 NC_073224.1 (229040553..229051589)

Chromosome 1 - NC_073224.2Genomic Context describing neighboring genes Neighboring gene basic proline-rich protein-like Neighboring gene spectrin beta chain, non-erythrocytic 5-like Neighboring gene calpain 9 Neighboring gene uncharacterized LOC129532020 Neighboring gene chromosome 1 C1orf198 homolog Neighboring gene uncharacterized LOC109027849

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of systemic arterial blood pressure by renin-angiotensin IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
angiotensinogen
Names
Serpin A8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001279625.1 → NP_001266554.1  angiotensinogen precursor

    See identical proteins and their annotated locations for NP_001266554.1

    Status: PROVISIONAL

    Source sequence(s)
    AF188488
    UniProtKB/TrEMBL
    G3QD84
    Related
    ENSGGOP00000000194.3, ENSGGOT00000000199.3
    Conserved Domains (1) summary
    cd02054
    Location:105 → 481
    angiotensinogen; Angiotensinogen is part of the renin-angiotensin system (RAS), which plays an important role in blood pressure regulation, renal haemodynamics, fluid and electrolyte homeostasis. It is also involved in normal and abnormal growth processes. The growth ...

RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073224.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    19420796..19431827 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GLP6.2 GenPept UniProtKB/Swiss-Prot:Q9GLP6

Gene LinkOut

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