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DDR1 discoidin domain receptor tyrosine kinase 1 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101133050, updated on 11-Apr-2024

Summary

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Gene symbol
DDR1
Gene description
discoidin domain receptor tyrosine kinase 1
See related
Ensembl:ENSGGOG00000014719
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 5 NC_073229.2 (48573771..48592826)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 6 NC_073230.1 (48356718..48380141)

Chromosome 5 - NC_073229.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134758663 Neighboring gene uncharacterized LOC109027235 Neighboring gene general transcription factor IIH subunit 4 Neighboring gene valyl-tRNA synthetase 2, mitochondrial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables collagen binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase collagen receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
epithelial discoidin domain-containing receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073229.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    48573771..48592826
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019029267.3 → XP_018884812.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A2I2ZSK0, G3RFJ9
    Conserved Domains (2) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  2. XM_019029266.3 → XP_018884811.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A2I2ZSK0, G3RFJ9
    Related
    ENSGGOP00000014367.3
    Conserved Domains (2) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  3. XM_004043601.4 → XP_004043649.1  epithelial discoidin domain-containing receptor 1 isoform X6

    See identical proteins and their annotated locations for XP_004043649.1

    UniProtKB/TrEMBL
    A0A2I2YE95, A0A2I2ZSK0
    Related
    ENSGGOP00000033216.1
    Conserved Domains (2) summary
    cd05096
    Location:567 → 870
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  4. XM_019029268.3 → XP_018884813.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A2I2ZSK0, G3RFJ9
    Conserved Domains (2) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  5. XM_055389949.1 → XP_055245924.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    G3RFJ9

  6. XM_055389950.2 → XP_055245925.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    G3RFJ9

  7. XM_055389956.2 → XP_055245931.1  epithelial discoidin domain-containing receptor 1 isoform X6

    UniProtKB/TrEMBL
    A0A2I2YE95

  8. XM_063707099.1 → XP_063563169.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    G3RFJ9

  9. XM_055389952.2 → XP_055245927.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    G3RFJ9

  10. XM_004043600.5 → XP_004043648.1  epithelial discoidin domain-containing receptor 1 isoform X3

    See identical proteins and their annotated locations for XP_004043648.1

    UniProtKB/TrEMBL
    A0A2I2ZSK0, G3RFJ9
    Conserved Domains (2) summary
    cd05096
    Location:604 → 907
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    cd00057
    Location:60 → 184
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  11. XM_004043604.4 → XP_004043652.1  epithelial discoidin domain-containing receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I2ZSK0
    Conserved Domains (2) summary
    cd05096
    Location:594 → 897
    PTKc_DDR1; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 1
    cd00057
    Location:87 → 211
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

  12. XM_063707098.1 → XP_063563168.1  epithelial discoidin domain-containing receptor 1 isoform X1

  13. XM_055389953.2 → XP_055245928.1  epithelial discoidin domain-containing receptor 1 isoform X3

    UniProtKB/TrEMBL
    G3RFJ9

  14. XM_055389948.2 → XP_055245923.2  epithelial discoidin domain-containing receptor 1 isoform X2

  15. XM_055389955.1 → XP_055245930.1  epithelial discoidin domain-containing receptor 1 isoform X5

RNA

  1. XR_010134071.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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