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PACSIN2 protein kinase C and casein kinase substrate in neurons 2 [ Ovis aries (sheep) ]

Gene ID: 101115867, updated on 8-Mar-2024

Summary

Gene symbol
PACSIN2
Gene description
protein kinase C and casein kinase substrate in neurons 2
See related
EnsemblRapid:ENSOARG00020000898
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (219610592..219722924, complement)

Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121818969 Neighboring gene ADP ribosylation factor GTPase activating protein 3 Neighboring gene uncharacterized LOC114113686 Neighboring gene TTL family tubulin polyglutamylase complex subunit L1 Neighboring gene mitochondrial import inner membrane translocase subunit TIM14-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in caveola assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in plasma membrane tubulation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protein kinase C and casein kinase substrate in neurons protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    219610592..219722924 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060414287.1XP_060270270.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X2

  2. XM_042247841.2XP_042103775.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3TKP6, A0A6P3YKT8, W5QCP7
    Conserved Domains (3) summary
    cd07679
    Location:18275
    F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
    cd11998
    Location:429484
    SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
    pfam16601
    Location:333428
    NPF; Rabosyn-5 repeating NPF sequence-motif
  3. XM_027968177.3XP_027823978.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X2

  4. XM_015095054.4XP_014950540.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3TKP6, A0A6P3YKT8, W5QCP7
    Related
    ENSOARP00020001045.1, ENSOART00020001270.2
    Conserved Domains (3) summary
    cd07679
    Location:18275
    F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
    cd11998
    Location:429484
    SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
    pfam16601
    Location:333428
    NPF; Rabosyn-5 repeating NPF sequence-motif
  5. XM_042247842.2XP_042103776.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3TKP6, A0A6P3YKT8, W5QCP7
    Conserved Domains (3) summary
    cd07679
    Location:18275
    F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
    cd11998
    Location:429484
    SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
    pfam16601
    Location:333428
    NPF; Rabosyn-5 repeating NPF sequence-motif
  6. XM_042247843.1XP_042103777.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3TKP6, A0A6P3YKT8, W5QCP7
    Conserved Domains (3) summary
    cd07679
    Location:18275
    F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
    cd11998
    Location:429484
    SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
    pfam16601
    Location:333428
    NPF; Rabosyn-5 repeating NPF sequence-motif
  7. XM_060414288.1XP_060270271.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X2

    Related
    ENSOARP00020001050.1, ENSOART00020001274.2
  8. XM_012175736.4XP_012031126.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

    See identical proteins and their annotated locations for XP_012031126.1

    UniProtKB/TrEMBL
    A0A6P3TKP6, A0A6P3YKT8, W5QCP7
    Related
    ENSOARP00020056371.1, ENSOART00020067782.1
    Conserved Domains (3) summary
    cd07679
    Location:18275
    F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
    cd11998
    Location:429484
    SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
    pfam16601
    Location:333428
    NPF; Rabosyn-5 repeating NPF sequence-motif
  9. XM_060414286.1XP_060270269.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3TKP6, A0A6P3YKT8, W5QCP7