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NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 [ Ovis aries (sheep) ]

Gene ID: 101115521, updated on 8-Mar-2024

Summary

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Gene symbol
NTMT1
Gene description
N-terminal Xaa-Pro-Lys N-methyltransferase 1
See related
EnsemblRapid:ENSOARG00020002110
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (6883185..6891603, complement)

Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114114127 Neighboring gene ankyrin repeat and SOCS box containing 6 Neighboring gene chromosome 3 C9orf50 homolog Neighboring gene uncharacterized LOC106991031

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-terminal protein N-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-terminal peptidyl-alanine methylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in N-terminal peptidyl-proline methylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in N-terminal peptidyl-serine methylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
N-terminal Xaa-Pro-Lys N-methyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    6883185..6891603 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027966311.2 → XP_027822112.1  N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P7DTJ3, W5PG28
    Conserved Domains (1) summary
    pfam05891
    Location:8 → 223
    Methyltransf_PK; AdoMet dependent proline di-methyltransferase

  2. XM_027966313.2 → XP_027822114.1  N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    W5PG28
    Related
    ENSOARP00020002668.2, ENSOART00020003217.2
    Conserved Domains (1) summary
    cl17173
    Location:8 → 209
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_027966310.2 → XP_027822111.1  N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P7DTJ3, W5PG28
    Conserved Domains (1) summary
    pfam05891
    Location:8 → 223
    Methyltransf_PK; AdoMet dependent proline di-methyltransferase

  4. XM_027966312.3 → XP_027822113.1  N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P7DTJ3, W5PG28
    Related
    ENSOARP00020045743.1, ENSOART00020080398.1
    Conserved Domains (1) summary
    pfam05891
    Location:8 → 223
    Methyltransf_PK; AdoMet dependent proline di-methyltransferase

  5. XM_027966314.3 → XP_027822115.1  N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X3

    Conserved Domains (1) summary
    cl17173
    Location:1 → 135
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Nucleotide Protein Strain
Heading Accession and Version

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