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MAS1 MAS1 proto-oncogene, G protein-coupled receptor [ Ovis aries (sheep) ]

Gene ID: 101112233, updated on 8-Mar-2024

Summary

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Gene symbol
MAS1
Gene description
MAS1 proto-oncogene, G protein-coupled receptor
See related
EnsemblRapid:ENSOARG00020006641
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 8 NC_056061.1 (83846164..83866384)

Chromosome 8 - NC_056061.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L18 Neighboring gene PARN like ribonuclease domain containing exonuclease 1 Neighboring gene insulin like growth factor 2 receptor Neighboring gene solute carrier family 22 member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056061.1 Chromosome 8 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells. Su Y, et al. Am J Physiol Renal Physiol, 2017 Jun 1. PMID 28228403, Free PMC Article
  2. Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep. Marshall AC, et al. Peptides, 2013 Jun. PMID 23538211, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The tubular Ang-(1-7)-Mas-NO pathway is attenuated in males and not females by antenatal betamethasone exposure.
    Title: Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells.
  2. Mas protein expression is significantly reduced in the medulla of adult sheep exposed to betamethasone in utero.
    Title: Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables angiotensin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene Mas
Names
MAS1 oncogene

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056061.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    83846164..83866384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012183209.5 → XP_012038599.1  proto-oncogene Mas

    See identical proteins and their annotated locations for XP_012038599.1

    UniProtKB/TrEMBL
    A0A6P3TVE4, W5NXQ6
    Related
    ENSOARP00020050298.1, ENSOART00020060413.1
    Conserved Domains (1) summary
    cd15110
    Location:33 → 307
    7tmA_MrgprH; mas-related G protein-coupled receptor subtype H, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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