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SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 [ Ovis aries (sheep) ]

Gene ID: 101111336, updated on 8-Mar-2024

Summary

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Gene symbol
SPSB3
Gene description
splA/ryanodine receptor domain and SOCS box containing 3
See related
EnsemblRapid:ENSOARG00020026298
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 24 NC_056077.1 (1877321..1882945, complement)

Chromosome 24 - NC_056077.1Genomic Context describing neighboring genes Neighboring gene NME/NM23 nucleoside diphosphate kinase 3 Neighboring gene mitochondrial ribosomal protein S34 Neighboring gene essential meiotic structure-specific endonuclease subunit 2 Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic Neighboring gene insulin like growth factor binding protein acid labile subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056077.1 Chromosome 24 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SPRY domain-containing SOCS box protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056077.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    1877321..1882945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015103856.3 → XP_014959342.2  SPRY domain-containing SOCS box protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A6P3YPX8
    Related
    ENSOARP00020034356.1, ENSOART00020041374.2
    Conserved Domains (2) summary
    cd03717
    Location:272 → 309
    SOCS_SOCS_like; SOCS (suppressors of cytokine signaling) box of SOCS-like proteins. The CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. These intracellular proteins regulate the responses of immune cells to ...
    cd12876
    Location:103 → 285
    SPRY_SOCS3; SPRY domain in the suppressor of cytokine signaling 3 (SOCS3) family

  2. XM_060406271.1 → XP_060262254.1  SPRY domain-containing SOCS box protein 3 isoform X1

  3. XM_060406270.1 → XP_060262253.1  SPRY domain-containing SOCS box protein 3 isoform X1

  4. XM_027962033.2 → XP_027817834.1  SPRY domain-containing SOCS box protein 3 isoform X3

Nucleotide Protein Strain
Heading Accession and Version

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