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PTK2B protein tyrosine kinase 2 beta [ Ovis aries (sheep) ]

Gene ID: 101106906, updated on 8-Mar-2024

Summary

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Gene symbol
PTK2B
Gene description
protein tyrosine kinase 2 beta
See related
EnsemblRapid:ENSOARG00020012073
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (38360028..38498089, complement)

Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene epoxide hydrolase 2 Neighboring gene cholinergic receptor nicotinic alpha 2 subunit Neighboring gene tripartite motif containing 35 Neighboring gene stathmin 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal complex assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein-tyrosine kinase 2-beta
Names
PTK2B protein tyrosine kinase 2 beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    38360028..38498089 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042243113.1 → XP_042099047.1  protein-tyrosine kinase 2-beta isoform X3

    Conserved Domains (3) summary
    cd05056
    Location:401 → 670
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2

  2. XM_027964310.2 → XP_027820111.1  protein-tyrosine kinase 2-beta isoform X5

    Related
    ENSOARP00020015907.1, ENSOART00020019231.2

  3. XM_027964309.2 → XP_027820110.1  protein-tyrosine kinase 2-beta isoform X4

  4. XM_027964308.2 → XP_027820109.1  protein-tyrosine kinase 2-beta isoform X2

    UniProtKB/TrEMBL
    A0A6P7DPT8, W5PIZ2
    Related
    ENSOARP00020015301.2, ENSOART00020018493.2
    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:872 → 1001
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain

  5. XM_027964304.2 → XP_027820105.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:874 → 1003
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain

  6. XM_042243110.1 → XP_042099044.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:874 → 1003
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain

  7. XM_042243108.1 → XP_042099042.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:874 → 1003
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain

  8. XM_042243112.1 → XP_042099046.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:874 → 1003
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain

  9. XM_027964307.3 → XP_027820108.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:874 → 1003
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain

  10. XM_042243109.2 → XP_042099043.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:874 → 1003
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain

  11. XM_042243111.2 → XP_042099045.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418 → 687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41 → 254
    B41; Band 4.1 homologues
    cd13190
    Location:261 → 368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:874 → 1003
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39 → 137
    FERM_N_2; FERM N-terminal domain
Nucleotide Protein Strain
Heading Accession and Version

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