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USP2 ubiquitin specific peptidase 2 [ Felis catus (domestic cat) ]

Gene ID: 101097757, updated on 8-Mar-2024

Summary

Official Symbol
USP2
Official Full Name
ubiquitin specific peptidase 2
Primary source
VGNC:VGNC:81096
See related
EnsemblRapid:ENSFCTG00005017486
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
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Genomic context

Location:
chromosome: D1
Exon count:
22
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D1 NC_058377.1 (16808873..16833762, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D1 NC_018732.3 (16773357..16798209, complement)

Chromosome D1 - NC_058377.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 5 Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene membrane frizzled-related protein Neighboring gene uncharacterized LOC123380364 Neighboring gene Thy-1 cell surface antigen Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ubiquitin carboxyl-terminal hydrolase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058377.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    16808873..16833762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019811415.3XP_019666974.2  ubiquitin carboxyl-terminal hydrolase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I2URI0
    Related
    ENSFCTP00005037170.1, ENSFCTT00005050892.1
    Conserved Domains (2) summary
    COG5560
    Location:266446
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:269598
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
  2. XM_006936725.5XP_006936787.2  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    UniProtKB/TrEMBL
    A0A337S1E0
    Related
    ENSFCTP00005037022.1, ENSFCTT00005050728.1
    Conserved Domains (2) summary
    COG5560
    Location:328508
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:331660
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
  3. XM_019811413.3XP_019666972.2  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    UniProtKB/TrEMBL
    A0A337S1E0
    Conserved Domains (2) summary
    COG5560
    Location:328508
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:331660
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
  4. XM_006936727.5XP_006936789.2  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    UniProtKB/TrEMBL
    A0A337S1E0
    Conserved Domains (2) summary
    COG5560
    Location:328508
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:331660
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
  5. XM_006936724.5XP_006936786.2  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    UniProtKB/TrEMBL
    A0A337S1E0
    Conserved Domains (2) summary
    COG5560
    Location:328508
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:331660
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
  6. XM_019811412.3XP_019666971.2  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    UniProtKB/TrEMBL
    A0A337S1E0
    Conserved Domains (2) summary
    COG5560
    Location:328508
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:331660
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
  7. XM_023239183.2XP_023094951.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X3

    UniProtKB/TrEMBL
    A0A337SNB2
    Related
    ENSFCTP00005036789.1, ENSFCTT00005050459.1
    Conserved Domains (1) summary
    pfam00443
    Location:58387
    UCH; Ubiquitin carboxyl-terminal hydrolase
  8. XM_011286406.3XP_011284708.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X6

    Related
    ENSFCTP00005036906.1, ENSFCTT00005050594.1
    Conserved Domains (1) summary
    pfam00443
    Location:14343
    UCH; Ubiquitin carboxyl-terminal hydrolase
  9. XM_045038416.1XP_044894351.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X4

    Conserved Domains (2) summary
    COG5560
    Location:34214
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:37366
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
  10. XM_045038417.1XP_044894352.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X5

    Conserved Domains (2) summary
    COG5560
    Location:16196
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02674
    Location:19348
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...