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APLP1 amyloid beta precursor like protein 1 [ Felis catus (domestic cat) ]

Gene ID: 101097529, updated on 8-Mar-2024

Summary

Official Symbol
APLP1
Official Full Name
amyloid beta precursor like protein 1
Primary source
VGNC:VGNC:67755
See related
EnsemblRapid:ENSFCTG00005026410
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
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Genomic context

Location:
chromosome: E2
Exon count:
17
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) E2 NC_058382.1 (17609129..17618752, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) E2 NC_018737.3 (17753640..17763303, complement)

Chromosome E2 - NC_058382.1Genomic Context describing neighboring genes Neighboring gene hematopoietic cell signal transducer Neighboring gene NFKB inhibitor delta Neighboring gene kirre like nephrin family adhesion molecule 2 Neighboring gene NPHS1 adhesion molecule, nephrin

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-2A adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables alpha-2B adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables alpha-2C adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transition metal ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058382.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    17609129..17618752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023245431.2XP_023101199.2  amyloid-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A5F5XX99
    Conserved Domains (2) summary
    smart00006
    Location:46211
    A4_EXTRA; amyloid A4
    COG4913
    Location:321464
    COG4913; Uncharacterized protein, contains a C-terminal ATPase domain [Function unknown]
  2. XM_023245430.2XP_023101198.2  amyloid-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F5XX99
    Conserved Domains (2) summary
    smart00006
    Location:46211
    A4_EXTRA; amyloid A4
    COG4913
    Location:321464
    COG4913; Uncharacterized protein, contains a C-terminal ATPase domain [Function unknown]
  3. XM_023245433.2XP_023101201.1  amyloid-like protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A5F5XX99
    Related
    ENSFCTP00005053040.1, ENSFCTT00005075438.1
    Conserved Domains (4) summary
    pfam05505
    Location:421544
    Ebola_NP; Ebola nucleoprotein
    pfam10515
    Location:586629
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12925
    Location:287469
    APP_E2; E2 domain of amyloid precursor protein
    cl26273
    Location:46211
    APP_N; Amyloid A4 N-terminal heparin-binding
  4. XM_023245434.2XP_023101202.1  amyloid-like protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A5F5XX99, A0A5F5Y3F3
    Conserved Domains (4) summary
    pfam05505
    Location:421543
    Ebola_NP; Ebola nucleoprotein
    pfam10515
    Location:585628
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12925
    Location:287469
    APP_E2; E2 domain of amyloid precursor protein
    cl26273
    Location:46211
    APP_N; Amyloid A4 N-terminal heparin-binding
  5. XM_023245432.2XP_023101200.1  amyloid-like protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A5F5XX99
    Related
    ENSFCTP00005052903.1, ENSFCTT00005075210.1
    Conserved Domains (4) summary
    pfam05505
    Location:421543
    Ebola_NP; Ebola nucleoprotein
    pfam10515
    Location:606649
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12925
    Location:287469
    APP_E2; E2 domain of amyloid precursor protein
    cl26273
    Location:46211
    APP_N; Amyloid A4 N-terminal heparin-binding
  6. XM_019818928.3XP_019674487.2  amyloid-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F5XX99, M3W5U5
    Related
    ENSFCTP00005052973.1, ENSFCTT00005075323.1
    Conserved Domains (4) summary
    pfam05505
    Location:421544
    Ebola_NP; Ebola nucleoprotein
    pfam10515
    Location:607650
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12925
    Location:287469
    APP_E2; E2 domain of amyloid precursor protein
    cl26273
    Location:46211
    APP_N; Amyloid A4 N-terminal heparin-binding