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LIFR LIF receptor subunit alpha [ Felis catus (domestic cat) ]

Gene ID: 101097206, updated on 8-Mar-2024

Summary

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Official Symbol
LIFR
Official Full Name
LIF receptor subunit alpha
Primary source
VGNC:VGNC:68045
See related
EnsemblRapid:ENSFCTG00005028217
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: A1
Exon count:
22
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A1 NC_058368.1 (208156764..208235886)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A1 NC_018723.3 (210821143..210899483)

Chromosome A1 - NC_058368.1Genomic Context describing neighboring genes Neighboring gene oncostatin M receptor Neighboring gene uncharacterized LOC111556514 Neighboring gene uncharacterized LOC109491920 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC123380207 Neighboring gene EGF like, fibronectin type III and laminin G domains Neighboring gene uncharacterized LOC123380208

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ciliary neurotrophic factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables leukemia inhibitory factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oncostatin-M receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leukemia inhibitory factor receptor
Names
LIF receptor alpha
leukemia inhibitory factor receptor alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058368.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    208156764..208235886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045037924.1 → XP_044893859.1  leukemia inhibitory factor receptor

    UniProtKB/TrEMBL
    A0A2I2UIE7, M3WPH0
    Related
    ENSFCTP00005055514.1, ENSFCTT00005079600.1
    Conserved Domains (2) summary
    cd00063
    Location:433 → 530
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam17971
    Location:131 → 244
    LIFR_D2; Leukemia inhibitory factor receptor D2 domain

  2. XM_023238979.2 → XP_023094747.2  leukemia inhibitory factor receptor

    UniProtKB/TrEMBL
    A0A2I2UIE7, M3WPH0
    Related
    ENSFCTP00005055684.1, ENSFCTT00005079878.1
    Conserved Domains (2) summary
    cd00063
    Location:433 → 530
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam17971
    Location:131 → 244
    LIFR_D2; Leukemia inhibitory factor receptor D2 domain

  3. XM_023238982.2 → XP_023094750.2  leukemia inhibitory factor receptor

    UniProtKB/TrEMBL
    A0A2I2UIE7, M3WPH0
    Conserved Domains (2) summary
    cd00063
    Location:433 → 530
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam17971
    Location:131 → 244
    LIFR_D2; Leukemia inhibitory factor receptor D2 domain
Nucleotide Protein
Heading Accession and Version

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