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HES1 hes family bHLH transcription factor 1 [ Felis catus (domestic cat) ]

Gene ID: 101091223, updated on 8-Mar-2024

Summary

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Official Symbol
HES1
Official Full Name
hes family bHLH transcription factor 1
Primary source
VGNC:VGNC:102756
See related
EnsemblRapid:ENSFCTG00005022220
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: C2
Exon count:
4
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) C2 NC_058376.1 (74308293..74310874, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) C2 NC_018731.3 (74647713..74650292, complement)

Chromosome C2 - NC_058376.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123379802 Neighboring gene uncharacterized LOC123379981 Neighboring gene uncharacterized LOC109503504 Neighboring gene uncharacterized LOC109503503

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing and comparative genomic analysis of 1227 Felis catus cDNA sequences enriched for developmental, clinical and nutritional phenotypes. Irizarry KJ, et al. BMC Genomics, 2012 Jan 18. PMID 22257742, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables E-box binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables N-box binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor HES-1
Names
hairy and enhancer of split 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058376.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    74308293..74310874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011285877.4 → XP_011284179.1  transcription factor HES-1

    UniProtKB/TrEMBL
    A0A337SWV8
    Related
    ENSFCTP00005046271.1, ENSFCTT00005063568.1
    Conserved Domains (2) summary
    cd11459
    Location:33 → 95
    bHLH-O_HES1_4; basic helix-loop-helix-orange (bHLH-O) domain found in hairy and enhancer of split HES-1, HES-4 and similar proteins
    pfam07527
    Location:110 → 148
    Hairy_orange; Hairy Orange
Nucleotide Protein
Heading Accession and Version

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