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JAK3 Janus kinase 3 [ Papio anubis (olive baboon) ]

Gene ID: 101014985, updated on 11-Apr-2024

Summary

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Gene symbol
JAK3
Gene description
Janus kinase 3
See related
Ensembl:ENSPANG00000004912
Gene type
protein coding
RefSeq status
MODEL
Organism
Papio anubis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
Orthologs
human mouse all
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Genomic context

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See JAK3 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
25
Annotation release Status Assembly Chr Location
104 current Panubis1.0 (GCF_008728515.1) 20 NC_044995.1 (34261501..34283664)
103 previous assembly Panu_3.0 (GCF_000264685.3) 19 NC_018170.2 (16350644..16367683, complement)

Chromosome 20 - NC_044995.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 5 member 5 Neighboring gene small nucleolar RNA SNORA68 Neighboring gene ribosomal protein L18a Neighboring gene insulin like 3 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase JAK3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Papio anubis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Panubis1.0 Primary Assembly

Genomic

  1. NC_044995.1 Reference Panubis1.0 Primary Assembly

    Range
    34261501..34283664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031659758.1 → XP_031515618.1  tyrosine-protein kinase JAK3 isoform X1

    UniProtKB/TrEMBL
    A0A0A0MVD8, A0A8I5NKU6
    Related
    ENSPANP00000006068.3, ENSPANT00000026551.3
    Conserved Domains (6) summary
    cd10380
    Location:405 → 501
    SH2_Jak3; Src homology 2 (SH2) domain in the Janus kinase 3 (Jak3) proteins
    cd05081
    Location:860 → 1142
    PTKc_Jak3_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 3
    pfam18377
    Location:169 → 288
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:69 → 156
    FERM_F1; FERM F1 ubiquitin-like domain
    cl17171
    Location:293 → 405
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:564 → 821
    PKc_like; Protein Kinases, catalytic domain

  2. XM_031659760.1 → XP_031515620.1  tyrosine-protein kinase JAK3 isoform X3

    Conserved Domains (5) summary
    cd10380
    Location:190 → 286
    SH2_Jak3; Src homology 2 (SH2) domain in the Janus kinase 3 (Jak3) proteins
    cd05081
    Location:645 → 927
    PTKc_Jak3_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 3
    pfam18377
    Location:1 → 73
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    cl17171
    Location:78 → 190
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:349 → 606
    PKc_like; Protein Kinases, catalytic domain

  3. XM_031659759.1 → XP_031515619.1  tyrosine-protein kinase JAK3 isoform X2

    Conserved Domains (6) summary
    cd10380
    Location:307 → 403
    SH2_Jak3; Src homology 2 (SH2) domain in the Janus kinase 3 (Jak3) proteins
    cd05081
    Location:762 → 1044
    PTKc_Jak3_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 3
    pfam18377
    Location:71 → 190
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:6 → 58
    FERM_F1; FERM F1 ubiquitin-like domain
    cl17171
    Location:195 → 307
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:466 → 723
    PKc_like; Protein Kinases, catalytic domain

  4. XM_031659761.1 → XP_031515621.1  tyrosine-protein kinase JAK3 isoform X3

    Conserved Domains (5) summary
    cd10380
    Location:190 → 286
    SH2_Jak3; Src homology 2 (SH2) domain in the Janus kinase 3 (Jak3) proteins
    cd05081
    Location:645 → 927
    PTKc_Jak3_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 3
    pfam18377
    Location:1 → 73
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    cl17171
    Location:78 → 190
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:349 → 606
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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