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SEMA7A semaphorin 7A (JohnMiltonHagen blood group) [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100979554, updated on 8-Mar-2024

Summary

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Gene symbol
SEMA7A
Gene description
semaphorin 7A (JohnMiltonHagen blood group)
See related
Ensembl:ENSPPAG00000036098
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 16 NC_073265.2 (63636920..63665516, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 15 NC_073264.1 (67800514..67825191, complement)

Chromosome 16 - NC_073265.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC130540851 Neighboring gene uncharacterized LOC134729115 Neighboring gene ubiquitin like 7 Neighboring gene uncharacterized LOC129394043 Neighboring gene small nucleolar RNA SNORD77

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemorepellent activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of axon extension involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neural crest cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axon extension IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage cytokine production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
semaphorin-7A
Names
semaphorin 7A (John Milton Hagen blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073265.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    63636920..63665516 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003811109.7 → XP_003811157.4  semaphorin-7A isoform X1

    UniProtKB/TrEMBL
    A0A2R9B8P0
    Conserved Domains (4) summary
    cd11243
    Location:70 → 489
    Sema_7A; The Sema domain, a protein interacting module, of semaphorin 7A (Sema7A, also called CD108)
    pfam01437
    Location:491 → 518
    PSI; Plexin repeat
    cd00096
    Location:547 → 553
    Ig; Ig strand A [structural motif]
    cl11960
    Location:547 → 617
    Ig; Immunoglobulin domain

  2. XM_034939131.4 → XP_034795022.1  semaphorin-7A isoform X2

    UniProtKB/TrEMBL
    A0A2R9BG37
    Conserved Domains (4) summary
    pfam01437
    Location:328 → 355
    PSI; Plexin repeat
    cd00096
    Location:384 → 390
    Ig; Ig strand A [structural motif]
    cl11960
    Location:384 → 454
    Ig; Immunoglobulin domain
    cl15693
    Location:1 → 326
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
Nucleotide Protein
Heading Accession and Version

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