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TRHDE thyrotropin releasing hormone degrading enzyme [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100977009, updated on 8-Mar-2024

Summary

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Gene symbol
TRHDE
Gene description
thyrotropin releasing hormone degrading enzyme
See related
Ensembl:ENSPPAG00000036451
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 10 NC_073259.2 (80300714..80696949)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 12 NC_073261.1 (80297114..80693349)

Chromosome 10 - NC_073259.2Genomic Context describing neighboring genes Neighboring gene magnesium transporter MRS2 homolog, mitochondrial-like Neighboring gene TBC1 domain family member 15 Neighboring gene tryptophan hydroxylase 2 Neighboring gene uncharacterized LOC130540673 Neighboring gene large ribosomal subunit protein eL31-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloaminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thyrotropin-releasing hormone-degrading ectoenzyme

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073259.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    80300714..80696949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003832902.6 → XP_003832950.4  thyrotropin-releasing hormone-degrading ectoenzyme

    UniProtKB/TrEMBL
    A0A2R9BJ06
    Conserved Domains (2) summary
    cd09601
    Location:190 → 635
    M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)
    pfam11838
    Location:720 → 1044
    ERAP1_C; ERAP1-like C-terminal domain
Nucleotide Protein
Heading Accession and Version

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