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ATR ATR serine/threonine kinase [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100975153, updated on 3-Apr-2024

Summary

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Gene symbol
ATR
Gene description
ATR serine/threonine kinase
See related
Ensembl:ENSPPAG00000042807
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
47
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 2 NC_085926.1 (140360351..140490134, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 3 NC_073252.1 (140365083..140494866, complement)

Chromosome 2 - NC_085926.1Genomic Context describing neighboring genes Neighboring gene 5'-3' exoribonuclease 1 Neighboring gene U6 spliceosomal RNA Neighboring gene U1 spliceosomal RNA Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 1-like Neighboring gene plastin 1 Neighboring gene transient receptor potential cation channel subfamily C member 1 Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase ATR
Names
ataxia telangiectasia and Rad3 related

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_085926.1 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    140360351..140490134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063602589.1 → XP_063458659.1  serine/threonine-protein kinase ATR isoform X3

  2. XM_003826518.4 → XP_003826566.2  serine/threonine-protein kinase ATR isoform X1

    UniProtKB/TrEMBL
    A0A2R9CEN3
    Conserved Domains (4) summary
    smart00802
    Location:1119 → 1224
    UME; Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
    COG5032
    Location:2133 → 2644
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd00892
    Location:2293 → 2567
    PIKKc_ATR; Catalytic domain of Ataxia telangiectasia and Rad3-related proteins
    pfam02259
    Location:1771 → 2092
    FAT; FAT domain

  3. XM_055110577.2 → XP_054966552.1  serine/threonine-protein kinase ATR isoform X2

Nucleotide Protein
Heading Accession and Version

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