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LRPAP1 LDL receptor related protein associated protein 1 [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100940462, updated on 8-Mar-2024

Summary

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Gene symbol
LRPAP1
Gene description
LDL receptor related protein associated protein 1
See related
Ensembl:ENSOGAG00000007628
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
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Genomic context

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See LRPAP1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852593.1 (2203211..2220721, complement)

NW_003852593.1Genomic Context describing neighboring genes Neighboring gene HGF activator Neighboring gene docking protein 7 Neighboring gene zinc finger protein 879 Neighboring gene glutamate metabotropic receptor 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003852593 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables low-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor antagonist activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables very-low-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of receptor internalization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of very-low-density lipoprotein particle clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cis-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum-Golgi intermediate compartment IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in rough endoplasmic reticulum lumen IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-2-macroglobulin receptor-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852593.1 Reference OtoGar3

    Range
    2203211..2220721 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003801139.3 → XP_003801187.1  alpha-2-macroglobulin receptor-associated protein isoform X2

    UniProtKB/TrEMBL
    H0WWQ4
    Related
    ENSOGAP00000006827.2, ENSOGAT00000007632.2
    Conserved Domains (5) summary
    cd14806
    Location:62 → 71
    RAP_D1; 3-helical coiled coil [structural motif]
    cd14807
    Location:151 → 248
    RAP_D2; Domain 2 of receptor-associated protein (RAP)
    cd14808
    Location:257 → 362
    RAP_D3; C-terminal receptor-associated protein (RAP), Domain 3
    pfam06400
    Location:29 → 134
    Alpha-2-MRAP_N; Alpha-2-macroglobulin RAP, N-terminal domain
    pfam06401
    Location:151 → 362
    Alpha-2-MRAP_C; Alpha-2-macroglobulin RAP, C-terminal domain

  2. XM_023507690.1 → XP_023363458.1  alpha-2-macroglobulin receptor-associated protein isoform X1

    Conserved Domains (3) summary
    cd14806
    Location:62 → 71
    RAP_D1; 3-helical coiled coil [structural motif]
    pfam06400
    Location:29 → 135
    Alpha-2-MRAP_N; Alpha-2-macroglobulin RAP, N-terminal domain
    pfam06401
    Location:152 → 363
    Alpha-2-MRAP_C; Alpha-2-macroglobulin RAP, C-terminal domain
Nucleotide Protein
Heading Accession and Version

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