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DCP2 decapping mRNA 2 [ Sarcophilus harrisii (Tasmanian devil) ]

Gene ID: 100922624, updated on 8-Mar-2024

Summary

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Gene symbol
DCP2
Gene description
decapping mRNA 2
See related
Ensembl:ENSSHAG00000001019
Gene type
protein coding
RefSeq status
MODEL
Organism
Sarcophilus harrisii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
103 current mSarHar1.11 (GCF_902635505.1) 1 NC_045426.1 (292117705..292194841)
102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 2 Unlocalized Scaffold NW_003824719.1 (6132..74613)

Chromosome 1 - NC_045426.1Genomic Context describing neighboring genes Neighboring gene transmembrane channel-like protein 1 Neighboring gene transmembrane channel-like protein 1 Neighboring gene MCC regulator of WNT signaling pathway Neighboring gene Na(+)/H(+) exchange regulatory cofactor NHE-RF1 pseudogene Neighboring gene DIRAS family GTPase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
m7GpppN-mRNA hydrolase
Names
DCP2 decapping enzyme homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSarHar1.11 Primary Assembly

Genomic

  1. NC_045426.1 Reference mSarHar1.11 Primary Assembly

    Range
    292117705..292194841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031943732.1 → XP_031799592.1  m7GpppN-mRNA hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A7N4V1N7, G3VD87
    Related
    ENSSHAP00000001141.2, ENSSHAT00000001156.2
    Conserved Domains (2) summary
    cd03672
    Location:97 → 246
    Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
    pfam05026
    Location:12 → 93
    DCP2; Dcp2, box A domain

  2. XM_031943742.1 → XP_031799602.1  m7GpppN-mRNA hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A7N4V1N7
    Related
    ENSSHAP00000032231.1, ENSSHAT00000042354.1
    Conserved Domains (2) summary
    cd03672
    Location:97 → 246
    Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
    pfam05026
    Location:12 → 93
    DCP2; Dcp2, box A domain
Nucleotide Protein
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