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GRB14 growth factor receptor bound protein 14 [ Capra hircus (goat) ]

Gene ID: 100861137, updated on 8-Mar-2024

Summary

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Gene symbol
GRB14
Gene description
growth factor receptor bound protein 14
See related
EnsemblRapid:ENSCHIG00000026062
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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See GRB14 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 2 NC_030809.1 (104447493..104573447, complement)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 2 NC_022294.1 (31042000..31166077)

Chromosome 2 - NC_030809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108633446 Neighboring gene fidgetin, microtubule severing factor Neighboring gene uncharacterized LOC102181440 Neighboring gene 60S ribosomal protein L10a pseudogene Neighboring gene cordon-bleu WH2 repeat protein like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
growth factor receptor-bound protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030809.1 Reference ASM170441v1 Primary Assembly

    Range
    104447493..104573447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018063930.1 → XP_017919419.1  growth factor receptor-bound protein 14 isoform X6

    UniProtKB/TrEMBL
    A0A452G5T3, A0A8C2P710
    Conserved Domains (4) summary
    cd10414
    Location:346 → 453
    SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
    cd01259
    Location:143 → 264
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16139
    Location:20 → 104
    RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
    pfam08947
    Location:283 → 327
    BPS; BPS (Between PH and SH2)

  2. XM_018063892.1 → XP_017919381.1  growth factor receptor-bound protein 14 isoform X1

    UniProtKB/TrEMBL
    A0A8C2P710
    Related
    ENSCHIP00000031919.2, ENSCHIT00000039794.2

  3. XM_018063912.1 → XP_017919401.1  growth factor receptor-bound protein 14 isoform X4

    UniProtKB/TrEMBL
    A0A8C2P710

  4. XM_018063899.1 → XP_017919388.1  growth factor receptor-bound protein 14 isoform X2

    UniProtKB/TrEMBL
    A0A452G5S5, A0A8C2P710
    Related
    ENSCHIP00000031909.1, ENSCHIT00000039784.2
    Conserved Domains (4) summary
    cd10414
    Location:433 → 540
    SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
    cd01259
    Location:230 → 351
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16139
    Location:107 → 191
    RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
    pfam08947
    Location:370 → 414
    BPS; BPS (Between PH and SH2)

  5. XM_018063904.1 → XP_017919393.1  growth factor receptor-bound protein 14 isoform X3

  6. XM_018063920.1 → XP_017919409.1  growth factor receptor-bound protein 14 isoform X5

Nucleotide Protein
Heading Accession and Version

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