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BMP3 bone morphogenetic protein 3 [ Canis lupus familiaris (dog) ]

Gene ID: 100855862, updated on 8-Mar-2024

Summary

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Official Symbol
BMP3provided by VGNC
Official Full Name
bone morphogenetic protein 3provided by VGNC
Primary source
VGNC:VGNC:57398
See related
Ensembl:ENSCAFG00845017996
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 32
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (5238247..5266418)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (36645845..36674004, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (34764153..34792337, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (5267894..5294547)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (5175043..5202995)

Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 299 Neighboring gene uncharacterized LOC119867173 Neighboring gene MICOS complex subunit MIC27-like Neighboring gene protein kinase cGMP-dependent 2 Neighboring gene RasGEF domain family member 1B Neighboring gene 60S ribosomal protein L37a-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Variation of BMP3 contributes to dog breed skull diversity. Schoenebeck JJ, et al. PLoS Genet, 2012. PMID 22876193, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Canine brachycephaly is caused by a missense mutation in the gene BMP3.
    Title: Variation of BMP3 contributes to dog breed skull diversity.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in osteoblast differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bone morphogenetic protein 3
Names
bone morphogenetic protein 3 (osteogenic)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051836.1 Reference ROS_Cfam_1.0

    Range
    5238247..5266418
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038443947.1 → XP_038299875.1  bone morphogenetic protein 3

    UniProtKB/TrEMBL
    A0A8C0KCR6, A0A8C0NIS2, A0A8I3PA06
    Related
    ENSCAFP00845024925.1, ENSCAFT00845031860.1
    Conserved Domains (1) summary
    cd19393
    Location:366 → 475
    TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049292.1 Alternate UMICH_Zoey_3.1

    Range
    5267894..5294547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038518348.1 → XP_038374276.1  bone morphogenetic protein 3

    Conserved Domains (1) summary
    cd19393
    Location:366 → 475
    TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

    Range
    5175043..5202995
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038646277.1 → XP_038502205.1  bone morphogenetic protein 3

    Conserved Domains (1) summary
    cd19393
    Location:366 → 475
    TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

    Range
    34764153..34792337 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038582313.1 → XP_038438241.1  bone morphogenetic protein 3

    UniProtKB/TrEMBL
    A0A8C0KCR6, A0A8C0NIS2, A0A8I3PA06
    Conserved Domains (1) summary
    cd19393
    Location:366 → 475
    TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    36645845..36674004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038462141.1 → XP_038318069.1  bone morphogenetic protein 3

    UniProtKB/TrEMBL
    A0A8C0KCR6, A0A8C0NIS2, A0A8I3PA06
    Conserved Domains (1) summary
    cd19393
    Location:366 → 475
    TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins
Nucleotide Protein
Heading Accession and Version

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