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Nedd4l NEDD4 like E3 ubiquitin protein ligase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100769118, updated on 8-Mar-2024

Summary

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Gene symbol
Nedd4l
Gene description
NEDD4 like E3 ubiquitin protein ligase
See related
Ensembl:ENSCGRG00015018716
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
24
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614238.1 (677429..734964, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (174063767..174387999, complement)

NW_003614238.1Genomic Context describing neighboring genes Neighboring gene alpha kinase 2 Neighboring gene small nuclear ribonucleoprotein-associated protein N-like Neighboring gene microRNA mir-122 Neighboring gene uncharacterized LOC103164111

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sodium channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase NEDD4-like; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase NEDD4-like
Names
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614238.1 Reference CriGri_1.0 Primary Assembly

    Range
    677429..734964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035458348.1 → XP_035314239.1  LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase NEDD4-like isoform X1

    UniProtKB/TrEMBL
    A0A8C2MPP0
    Conserved Domains (5) summary
    smart00456
    Location:411 → 443
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:504 → 836
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    PHA03247
    Location:195 → 364
    PHA03247; large tegument protein UL36; Provisional
    pfam00397
    Location:263 → 292
    WW; WW domain
    cl14603
    Location:1 → 32
    C2; C2 domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048595.1 Alternate CriGri-PICRH-1.0

    Range
    174063767..174387999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027402751.2 → XP_027258552.1  E3 ubiquitin-protein ligase NEDD4-like isoform X2

    UniProtKB/TrEMBL
    A0A8C2MPP0, A0A9J7FF26
    Related
    ENSCGRP00015024875.1, ENSCGRT00015030504.2

  2. XM_035440119.1 → XP_035296010.1  E3 ubiquitin-protein ligase NEDD4-like isoform X3

    UniProtKB/TrEMBL
    A0A8C2MPP0, A0A9J7JUU2
    Conserved Domains (4) summary
    smart00456
    Location:409 → 441
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:502 → 831
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    pfam00397
    Location:247 → 276
    WW; WW domain
    cl14603
    Location:1 → 32
    C2; C2 domain
Nucleotide Protein Strain
Heading Accession and Version

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