U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nlrp12 NLR family pyrin domain containing 12 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100762367, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Nlrp12
Gene description
NLR family pyrin domain containing 12
See related
Ensembl:ENSCGRG00015011101
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Nlrp12 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
11
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614747.1 (47408..68891, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 9 NC_048602.1 (21160346..21181795, complement)

NW_003614747.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor 49 Neighboring gene myeloid associated differentiation marker

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to cytokine stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class I biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
NACHT, LRR and PYD domains-containing protein 12

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614747.1 Reference CriGri_1.0 Primary Assembly

    Range
    47408..68891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035460602.1 → XP_035316493.1  NACHT, LRR and PYD domains-containing protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C2M5F7
    Conserved Domains (7) summary
    cd00116
    Location:606 → 897
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:637 → 662
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:665 → 690
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam02758
    Location:12 → 86
    PYRIN; PAAD/DAPIN/Pyrin domain
    pfam17776
    Location:414 → 521
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam17779
    Location:359 → 412
    NOD2_WH; NOD2 winged helix domain
    cl40481
    Location:210 → 280
    YlqF_related_GTPase; Circularly permuted YlqF-related GTPases

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048602.1 Alternate CriGri-PICRH-1.0

    Range
    21160346..21181795 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027431021.2 → XP_027286822.1  NACHT, LRR and PYD domains-containing protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C2M5F7, A0A9J7GHE3
    Related
    ENSCGRP00015014452.1, ENSCGRT00015017715.2
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.