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Cit citron rho-interacting serine/threonine kinase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100755517, updated on 8-Mar-2024

Summary

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Gene symbol
Cit
Gene description
citron rho-interacting serine/threonine kinase
Locus tag
I79_001222
See related
Ensembl:ENSCGRG00015003018
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
50
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613605.1 (4061660..4237138, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (95915906..96091228)

NW_003613605.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 60 Neighboring gene transmembrane protein 233 Neighboring gene U6 spliceosomal RNA Neighboring gene protein kinase AMP-activated non-catalytic subunit beta 1 Neighboring gene BICD family like cargo adaptor 1 Neighboring gene RAB35, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
citron Rho-interacting kinase
Names
Citron Rho-interacting kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613605.1 Reference CriGri_1.0 Primary Assembly

    Range
    4061660..4237138 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016976877.2 → XP_016832366.1  citron Rho-interacting kinase isoform X6

    UniProtKB/TrEMBL
    A0A9J7FXJ8, G3GU69
    Conserved Domains (6) summary
    smart00036
    Location:1672 → 1968
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:97 → 359
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1196
    Location:473 → 1372
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00029
    Location:1442 → 1490
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd05601
    Location:96 → 421
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1523 → 1642
    PH; PH domain

  2. XM_035457545.1 → XP_035313436.1  citron Rho-interacting kinase isoform X8

    UniProtKB/TrEMBL
    A0A9J7GWA8, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1650 → 1946
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1350
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1501 → 1620
    PH; PH domain
    cd20814
    Location:1416 → 1471
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  3. XM_035457553.1 → XP_035313444.1  citron Rho-interacting kinase isoform X11

    UniProtKB/TrEMBL
    A0A9J7GWI4, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1665 → 1961
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1365
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1516 → 1635
    PH; PH domain
    cd20814
    Location:1431 → 1486
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  4. XM_035457543.1 → XP_035313434.1  citron Rho-interacting kinase isoform X7

    UniProtKB/TrEMBL
    A0A9J7GZ69, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1665 → 1961
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1365
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1516 → 1635
    PH; PH domain
    cd20814
    Location:1431 → 1486
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  5. XM_035457534.1 → XP_035313425.1  citron Rho-interacting kinase isoform X5

    UniProtKB/TrEMBL
    A0A9J7GV96, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1674 → 1970
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1374
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1525 → 1644
    PH; PH domain
    cd20814
    Location:1440 → 1495
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  6. XM_035457520.1 → XP_035313411.1  citron Rho-interacting kinase isoform X3

    UniProtKB/TrEMBL
    A0A9J7GXW8, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1694 → 1990
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1394
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1545 → 1664
    PH; PH domain
    cd20814
    Location:1460 → 1515
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  7. XM_035457525.1 → XP_035313416.1  citron Rho-interacting kinase isoform X4

    UniProtKB/TrEMBL
    A0A9J7GXJ2, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1688 → 1984
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1388
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1539 → 1658
    PH; PH domain
    cd20814
    Location:1454 → 1509
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  8. XM_035457512.1 → XP_035313403.1  citron Rho-interacting kinase isoform X2

    UniProtKB/TrEMBL
    A0A9J7K7Q7, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1703 → 1999
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1403
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1554 → 1673
    PH; PH domain
    cd20814
    Location:1469 → 1524
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  9. XM_016976884.2 → XP_016832373.2  citron Rho-interacting kinase isoform X1

    UniProtKB/TrEMBL
    A0A9J7FVR6, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1703 → 1999
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1403
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1554 → 1673
    PH; PH domain
    cd20814
    Location:1469 → 1524
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  10. XM_016976870.3 → XP_016832359.1  citron Rho-interacting kinase isoform X6

    UniProtKB/TrEMBL
    A0A9J7FXJ8, G3GU69
    Conserved Domains (6) summary
    smart00036
    Location:1672 → 1968
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:97 → 359
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1196
    Location:473 → 1372
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00029
    Location:1442 → 1490
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd05601
    Location:96 → 421
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1523 → 1642
    PH; PH domain

  11. XM_027438372.1 → XP_027294173.1  citron Rho-interacting kinase isoform X10

    UniProtKB/TrEMBL
    A0A9J7FZW7

  12. XM_035457547.1 → XP_035313438.1  citron Rho-interacting kinase isoform X9

    UniProtKB/TrEMBL
    A0A9J7K4C4, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1703 → 1999
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1403
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1554 → 1673
    PH; PH domain
    cd20814
    Location:1469 → 1524
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    95915906..96091228
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027414197.2 → XP_027269998.1  citron Rho-interacting kinase isoform X6

    UniProtKB/TrEMBL
    A0A9J7FXJ8, G3GU69
    Related
    ENSCGRP00015043139.1, ENSCGRT00015051688.1

  2. XM_027414198.2 → XP_027269999.2  citron Rho-interacting kinase isoform X1

    UniProtKB/TrEMBL
    A0A9J7FVR6, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1703 → 1999
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1403
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1554 → 1673
    PH; PH domain
    cd20814
    Location:1469 → 1524
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  3. XM_035443253.1 → XP_035299144.1  citron Rho-interacting kinase isoform X2

    UniProtKB/TrEMBL
    A0A9J7K7Q7, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1703 → 1999
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1403
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1554 → 1673
    PH; PH domain
    cd20814
    Location:1469 → 1524
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  4. XM_035443255.1 → XP_035299146.1  citron Rho-interacting kinase isoform X4

    UniProtKB/TrEMBL
    A0A9J7GXJ2, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1688 → 1984
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1388
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1539 → 1658
    PH; PH domain
    cd20814
    Location:1454 → 1509
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  5. XM_035443254.1 → XP_035299145.1  citron Rho-interacting kinase isoform X3

    UniProtKB/TrEMBL
    A0A9J7GXW8, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1694 → 1990
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1394
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1545 → 1664
    PH; PH domain
    cd20814
    Location:1460 → 1515
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  6. XM_035443256.1 → XP_035299147.1  citron Rho-interacting kinase isoform X5

    UniProtKB/TrEMBL
    A0A9J7GV96, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1674 → 1970
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1374
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1525 → 1644
    PH; PH domain
    cd20814
    Location:1440 → 1495
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  7. XM_035443257.1 → XP_035299148.1  citron Rho-interacting kinase isoform X7

    UniProtKB/TrEMBL
    A0A9J7GZ69, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1665 → 1961
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1365
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1516 → 1635
    PH; PH domain
    cd20814
    Location:1431 → 1486
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  8. XM_035443260.1 → XP_035299151.1  citron Rho-interacting kinase isoform X11

    UniProtKB/TrEMBL
    A0A9J7GWI4, G3GU69
    Conserved Domains (5) summary
    smart00036
    Location:1665 → 1961
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1365
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1516 → 1635
    PH; PH domain
    cd20814
    Location:1431 → 1486
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  9. XM_035443258.1 → XP_035299149.1  citron Rho-interacting kinase isoform X8

    UniProtKB/TrEMBL
    A0A9J7GWA8, G3GU69
    Related
    ENSCGRP00015004480.2, ENSCGRT00015005553.2
    Conserved Domains (5) summary
    smart00036
    Location:1650 → 1946
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1350
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1501 → 1620
    PH; PH domain
    cd20814
    Location:1416 → 1471
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  10. XM_035443259.1 → XP_035299150.1  citron Rho-interacting kinase isoform X9

    UniProtKB/TrEMBL
    A0A9J7K4C4, G3GU69
    Related
    ENSCGRP00015004468.2, ENSCGRT00015005538.2
    Conserved Domains (5) summary
    smart00036
    Location:1703 → 1999
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:504 → 1403
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:127 → 452
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1554 → 1673
    PH; PH domain
    cd20814
    Location:1469 → 1524
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  11. XM_027414196.2 → XP_027269997.1  citron Rho-interacting kinase isoform X6

    UniProtKB/TrEMBL
    A0A9J7FXJ8, G3GU69

  12. XM_027414207.1 → XP_027270008.1  citron Rho-interacting kinase isoform X10

    UniProtKB/TrEMBL
    A0A9J7FZW7
Nucleotide Protein Strain
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