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Lpin2 lipin 2 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100716519, updated on 8-Mar-2024

Summary

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Gene symbol
Lpin2
Gene description
lipin 2
See related
Ensembl:ENSCPOG00000023844
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947503.1 (61604555..61672046, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176337.1 (7151787..7219278)

NW_026947503.1Genomic Context describing neighboring genes Neighboring gene structural maintenance of chromosomes flexible hinge domain containing 1 Neighboring gene uncharacterized LOC134471828 Neighboring gene elastin microfibril interfacer 2 Neighboring gene myomesin 1 Neighboring gene 26S proteasome regulatory subunit 10B Neighboring gene uncharacterized LOC134471829

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triglyceride biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidate phosphatase LPIN2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947503.1 Reference mCavPor4.1

    Range
    61604555..61672046 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003464445.5 → XP_003464493.2  phosphatidate phosphatase LPIN2 isoform X3

    UniProtKB/TrEMBL
    H0W6P4
    Related
    ENSCPOP00000018648.2
    Conserved Domains (4) summary
    pfam15017
    Location:862 → 882
    AF1Q; Drug resistance and apoptosis regulator
    pfam04571
    Location:1 → 106
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:623 → 848
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:460 → 550
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  2. XM_023562721.2 → XP_023418489.1  phosphatidate phosphatase LPIN2 isoform X2

    Conserved Domains (4) summary
    pfam04571
    Location:34 → 140
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:656 → 852
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:865 → 883
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:493 → 583
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  3. XM_063231902.1 → XP_063087972.1  phosphatidate phosphatase LPIN2 isoform X4

  4. XM_013146701.3 → XP_013002155.1  phosphatidate phosphatase LPIN2 isoform X1

    UniProtKB/TrEMBL
    A0A286XQH3
    Related
    ENSCPOP00000027778.1
    Conserved Domains (4) summary
    pfam15017
    Location:895 → 915
    AF1Q; Drug resistance and apoptosis regulator
    pfam04571
    Location:34 → 139
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:656 → 881
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:493 → 583
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
Nucleotide Protein
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