mef2d myocyte enhancer factor 2d [Oreochromis niloticus (Nile tilapia)] - Gene

Summary

Gene symbol: mef2d
Gene description: myocyte enhancer factor 2d
See related: Ensembl:ENSONIG00000001554
Gene type: protein coding
RefSeq status: MODEL
Organism: Oreochromis niloticus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Expression: Broad expression in skeletal muscle (RPKM 21.4), brain (RPKM 14.5) and 8 other tissues See more
Orthologs: human zebrafish all
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Genomic context

Location:: chromosome: LG11

Exon count:: 16

Annotation release	Status	Assembly	LG	Location
104	current	O_niloticus_UMD_NMBU (GCF_001858045.2)	LG11	NC_031976.2 (30097278..30199896)
103	previous assembly	ASM185804v2 (GCF_001858045.1)	LG11	NC_031976.1 (11175766..11278414)

Linkage Group LG11 - NC_031976.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Oreochromis niloticus Transcriptome or Gene expression
Description: Oreochromis niloticus (Nile Tilapia) RNA sequencing from multiple tissues.
BioProject: PRJNA78915
Analysis date: Fri Dec 29 00:23:36 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables histone deacetylase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: myocyte-specific enhancer factor 2D

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

NC_031976.2 Reference O_niloticus_UMD_NMBU Primary Assembly

Range

30097278..30199896

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_025911272.1 → XP_025767057.1 myocyte-specific enhancer factor 2D isoform X1

UniProtKB/TrEMBL

A0A669E8G7

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_025911275.1 → XP_025767060.1 myocyte-specific enhancer factor 2D isoform X2

UniProtKB/TrEMBL

A0A669E8G7

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_025911277.1 → XP_025767062.1 myocyte-specific enhancer factor 2D isoform X4

UniProtKB/TrEMBL

A0A669CUV8

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_005472773.4 → XP_005472830.1 myocyte-specific enhancer factor 2D isoform X5

UniProtKB/TrEMBL

A0A669E8G7

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_005472775.4 → XP_005472832.1 myocyte-specific enhancer factor 2D isoform X6

UniProtKB/TrEMBL

A0A669EG07

Related

ENSONIP00000070474.1, ENSONIT00000066133.1

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_025911276.1 → XP_025767061.1 myocyte-specific enhancer factor 2D isoform X3

UniProtKB/TrEMBL

A0A669E8G7, A0A669ECS4

Related

ENSONIP00000068836.1, ENSONIT00000054106.1

Conserved Domains (1) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_003456416.5 → XP_003456464.1 myocyte-specific enhancer factor 2D isoform X7

UniProtKB/TrEMBL

A0A669B1J9

Related

ENSONIP00000052158.1, ENSONIT00000039436.1

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:118 → 148

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_025911274.1 → XP_025767059.1 myocyte-specific enhancer factor 2D isoform X1

UniProtKB/TrEMBL

A0A669E8G7

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_025911273.1 → XP_025767058.1 myocyte-specific enhancer factor 2D isoform X1

UniProtKB/TrEMBL

A0A669E8G7

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat