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hic1 hypermethylated in cancer 1 [ Oreochromis niloticus (Nile tilapia) ]

Gene ID: 100694398, updated on 8-Mar-2024

Summary

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Gene symbol
hic1
Gene description
hypermethylated in cancer 1
See related
Ensembl:ENSONIG00000021060
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis niloticus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Expression
Broad expression in heart (RPKM 6.5), kidney (RPKM 6.2) and 8 other tissues See more
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG14
Exon count:
3
Annotation release Status Assembly LG Location
104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG14 NC_031979.2 (26995005..27010374)
103 previous assembly ASM185804v2 (GCF_001858045.1) LG14 NC_031979.1 (13837038..13852416, complement)

Linkage Group LG14 - NC_031979.2Genomic Context describing neighboring genes Neighboring gene TAO kinase 1a Neighboring gene TSR1 ribosome maturation factor Neighboring gene uncharacterized LOC102081189 Neighboring gene uncharacterized LOC112842160 Neighboring gene diphthamide biosynthesis 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Oreochromis niloticus Transcriptome or Gene expression
  • Description: Oreochromis niloticus (Nile Tilapia) RNA sequencing from multiple tissues.
  • BioProject: PRJNA78915
  • Analysis date: Fri Dec 29 00:23:36 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypermethylated in cancer 1 protein
Names
HIC ZBTB transcriptional repressor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

  1. NC_031979.2 Reference O_niloticus_UMD_NMBU Primary Assembly

    Range
    26995005..27010374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005474730.4 → XP_005474787.1  hypermethylated in cancer 1 protein isoform X3

    See identical proteins and their annotated locations for XP_005474787.1

    UniProtKB/TrEMBL
    I3KZ16
    Conserved Domains (6) summary
    smart00225
    Location:29 → 126
    BTB; Broad-Complex, Tramtrack and Bric a brac
    COG5048
    Location:577 → 625
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:553 → 573
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:551 → 573
    zf-C2H2; Zinc finger, C2H2 type
    pfam00651
    Location:18 → 123
    BTB; BTB/POZ domain
    pfam13465
    Location:594 → 618
    zf-H2C2_2; Zinc-finger double domain

  2. XM_005474729.3 → XP_005474786.1  hypermethylated in cancer 1 protein isoform X3

    See identical proteins and their annotated locations for XP_005474786.1

    UniProtKB/TrEMBL
    I3KZ16
    Conserved Domains (6) summary
    smart00225
    Location:29 → 126
    BTB; Broad-Complex, Tramtrack and Bric a brac
    COG5048
    Location:577 → 625
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:553 → 573
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:551 → 573
    zf-C2H2; Zinc finger, C2H2 type
    pfam00651
    Location:18 → 123
    BTB; BTB/POZ domain
    pfam13465
    Location:594 → 618
    zf-H2C2_2; Zinc-finger double domain

  3. XM_005474728.4 → XP_005474785.1  hypermethylated in cancer 1 protein isoform X2

    Conserved Domains (6) summary
    smart00225
    Location:42 → 139
    BTB; Broad-Complex, Tramtrack and Bric a brac
    COG5048
    Location:590 → 638
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:566 → 586
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:564 → 586
    zf-C2H2; Zinc finger, C2H2 type
    pfam00651
    Location:31 → 136
    BTB; BTB/POZ domain
    pfam13465
    Location:607 → 631
    zf-H2C2_2; Zinc-finger double domain

  4. XM_005474727.4 → XP_005474784.1  hypermethylated in cancer 1 protein isoform X1

    UniProtKB/TrEMBL
    I3KZ16
    Related
    ENSONIP00000026363.2, ENSONIT00000026386.2
    Conserved Domains (6) summary
    smart00225
    Location:52 → 149
    BTB; Broad-Complex, Tramtrack and Bric a brac
    COG5048
    Location:600 → 648
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:576 → 596
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:574 → 596
    zf-C2H2; Zinc finger, C2H2 type
    pfam00651
    Location:41 → 146
    BTB; BTB/POZ domain
    pfam13465
    Location:617 → 641
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version

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