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Prdx1 peroxiredoxin 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100689332, updated on 8-Mar-2024

Summary

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Gene symbol
Prdx1
Gene description
peroxiredoxin 1
See related
Ensembl:ENSCGRG00015024883
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as
TDPX2; TPX-2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
6
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613647.1 (2246754..2256610)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (35700206..35707786, complement)

NW_003613647.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 17 Neighboring gene nuclear autoantigenic sperm protein Neighboring gene aldo-keto reductase family 1 member A1 Neighboring gene metabolism of cobalamin associated C Neighboring gene CCDC163 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of galectin I and thioredoxin peroxidase II as two arsenic-binding proteins in Chinese hamster ovary cells. Chang KN, et al. Biochem J, 2003 Apr 15. PMID 12519079, Free PMC Article
  2. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells. Zhang M, et al. Mol Cell Proteomics, 2014 Nov. PMID 25044020, Free PMC Article
  3. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thioredoxin peroxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leukocyte activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in removal of superoxide radicals IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peroxiredoxin-1
Names
Thioredoxin peroxidase 2
thioredoxin peroxidase II
thioredoxin-dependent peroxiredoxin 1
NP_001233694.1
XP_007608925.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001246765.1 → NP_001233694.1  peroxiredoxin-1

    See identical proteins and their annotated locations for NP_001233694.1

    Status: PROVISIONAL

    Source sequence(s)
    AF221841
    UniProtKB/Swiss-Prot
    Q9JKY1
    UniProtKB/TrEMBL
    A0A8C2MUU1
    Related
    ENSCGRP00015033003.1, ENSCGRT00015040258.2
    Conserved Domains (2) summary
    PTZ00253
    Location:1 → 196
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:8 → 180
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613647.1 Reference CriGri_1.0 Primary Assembly

    Range
    2246754..2256610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007610735.4 → XP_007608925.1  peroxiredoxin-1 isoform X1

    See identical proteins and their annotated locations for XP_007608925.1

    UniProtKB/TrEMBL
    A0A8C2MUU1, G3GYP9
    Conserved Domains (2) summary
    PTZ00253
    Location:1 → 196
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:8 → 180
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048595.1 Alternate CriGri-PICRH-1.0

    Range
    35700206..35707786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9JKY1.1 GenPept UniProtKB/Swiss-Prot:Q9JKY1

Gene LinkOut

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