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CFL2 cofilin 2 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100663505, updated on 11-Apr-2024

Summary

Gene symbol
CFL2
Gene description
cofilin 2
See related
EnsemblRapid:ENSLAFG00000010579
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
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Genomic context

Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 10 NC_087351.1 (46696368..46699135, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573429.1 (10364135..10368638, complement)

Chromosome 10 - NC_087351.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene sorting nexin 6 Neighboring gene uncharacterized LOC111750150 Neighboring gene bromodomain adjacent to zinc finger domain 1A Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC100664073

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in actin filament fragmentation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in actin filament severing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in actin cortical patch IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087351.1 Reference mLoxAfr1.hap2

    Range
    46696368..46699135 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010588586.2XP_010586888.1  cofilin-2

    See identical proteins and their annotated locations for XP_010586888.1

    UniProtKB/TrEMBL
    G3T5W2
    Related
    ENSLAFP00000038723.1, ENSLAFT00000044626.1
    Conserved Domains (1) summary
    cd11286
    Location:3153
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors